Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric Patient [PDF]
Malignant acanthosis nigricans (AN) is a rare paraneoplastic syndrome seen primarily in adults with an underlying diagnosis of gastrointestinal adenocarcinoma.
Elizabeth Isaacoff +5 more
doaj +6 more sources
Clinical prognostic factors in pediatric adrenocortical tumors: A meta‐analysis [PDF]
AbstractPediatric adrenocortical tumors (ACT) are rare and sometimes aggressive malignancies, but there is no consensus on the outcome predictors in children. A systematic search of MEDLINE, SCOPUS, Web of Science, and the Cochrane Library for studies from 1994 to 2020 about pediatric ACT was performed.
Elisa Zambaiti +6 more
openaire +4 more sources
Retroperitoneoscopic adrenalectomy in an infant with adrenocortical virilizing tumor
CONTEXT: Adrenocortical virilizing tumors are rare in the pediatric age group. Laparoscopic surgery is the gold standard method for treatment of adrenal functional tumors under 6 cm in size, in adults.
Marcos Tobias-Machado +8 more
doaj +2 more sources
Expression of Insulin-Like Growth Factor-II and Its Receptor in Pediatric and Adult Adrenocortical Tumors [PDF]
Adrenocortical tumors are heterogeneous neoplasms with incompletely understood pathogenesis. IGF-II overexpression has been consistently demonstrated in adult adrenocortical carcinomas.The objective of the study was to analyze expression of IGF-II and its receptor (IGF-IR) in pediatric and adult adrenocortical tumors and the effects of a selective IGF ...
Madson Q, Almeida +11 more
openaire +3 more sources
DNA Methylation Profiling Reveals Prognostically Significant Groups in Pediatric Adrenocortical Tumors: A Report From the International Pediatric Adrenocortical Tumor Registry. [PDF]
PURPOSE Pediatric adrenocortical carcinomas (ACCs) are aggressive; the overall survival of patients with ACCs is 40%-50%. Appropriate staging and histologic classification are crucial because children with incomplete resections, metastases, or relapsed disease have a dismal prognosis.
Clay MR +11 more
europepmc +4 more sources
MicroRNA expression profile predicts prognosis of pediatric adrenocortical tumors [PDF]
Pediatric adrenocortical tumors (ACT) are rare aggressive neoplasms with heterogeneous prognosis. Despite extensive efforts, identifying reliable prognostic factors for pediatric patients with ACT remains a challenge. MicroRNA (miRNA) signatures have been associated with cancer diagnosis, treatment response, and prognosis of several types of cancer ...
Luciana Chain Veronez +16 more
openaire +2 more sources
Adrenocortical tumor in 20 months old female
Adrecortical virilizing tumors are rare in the pediatric age group. There is 1% incidence for adneral cancer. In comparison with adult patients , there is function adrenalectomy tumor in pediatric group.
Mohammad Reza Darabi Mahboob (MD) +1 more
doaj +1 more source
Pediatric adrenal incidentaloma as a rare and difficult to diagnose finding - review
Adrenal incidentaloma (AI) is an asymptomatic mass localized in the adrenal gland, usually detected during diagnostic imaging performed due to other health issues than the suspected adrenal disease.
Dominika Pałac +3 more
doaj +1 more source
Clinical and molecular aspects of a pediatric metachronous adrenocortical tumor [PDF]
The occurrence of metachronous adrenocortical carcinoma has rarely been described. We report a case of a child with virilizing adrenocortical metachronous tumors that, despite several metastases, presented long-term survival (15 years). We analyzed in this tumor IGF2, IGF1R and FGFR4 gene expression, and evaluated the presence of p.R337H germline p53 ...
Lima, Lorena de Oliveira +8 more
openaire +4 more sources
IGF2 and IGF1R in pediatric adrenocortical tumors: roles in metastasis and steroidogenesis [PDF]
Deregulation of the IGF system observed in human tumors indicates a role in malignant cell transformation and in tumor cell proliferation. Although overexpression of the IGF2 and IGF1R genes was described in adrenocortical tumors (ACTs), few studies ...
Régia Caroline, Peixoto Lira +16 more
openaire +2 more sources

