Results 51 to 60 of about 10,162 (212)

N6-methyladenosine regulates PEDV replication and host gene expression

Virology, 2020
Methylation of the N6 position of adenosine (m6A) is a widespread RNA modification that is critical for various physiological and pathological processes. Although this modification was also found in the RNA of several viruses almost 40 years ago, its biological functions during viral infection have been elucidated recently.
Jianing Chen, Li Jin, Zemei Wang, Liyuan Wang, Qingbo Chen, Yaru Cui, Guangliang Liu   +6 more
openaire   +2 more sources

Combining herbal fermentation with Lactobacillus expressing recombinant PEDV-S1 protein offers protection against PEDV infection

Animals and Zoonoses
The porcine epidemic diarrhea virus (PEDV) causes porcine epidemic diarrhea, an acute, highly contagious infectious disease that has caused significant economic losses in the global pig industry. Due to the high variability of PEDV, vaccines based on classical strains no longer provide effective immune protection, and no specific antiviral drugs have ...
Jiaxing Zhan, Tianxin Yu, Haixu Wang, Yibo Zhao, Yan Zeng, Chunfeng Wang, Xin Cao   +6 more
openaire   +2 more sources

Inactivated Pseudomonas PE(ΔIII) exotoxin fused to neutralizing epitopes of PEDV S proteins produces a specific immune response in mice

Animal Diseases, 2021
Porcine epidemic diarrhea (PED) caused by the porcine epidemic diarrhea virus (PEDV), is a severe infectious and devastating swine disease that leads to serious economic losses in the swine industry worldwide.
Leqiang Sun, Yajie Tang, Keji Yan, Huanchun Chen, Huawei Zhang   +4 more
doaj   +1 more source

RSL3 Inhibits Porcine Epidemic Diarrhea Virus Replication by Activating Ferroptosis

Viruses, 2023
Porcine epidemic diarrhea virus (PEDV) is a highly contagious coronavirus that induces diarrhea and death in neonatal piglets, resulting in substantial economic losses to the global swine industry.
Yingguang Li, Yuwei Bao, Yan Li, Xiaoxiao Duan, Shaoming Dong, Jiaxu Lin, Xiaoyun Chang, Yue Tan, Hongliang Zhang, Hu Shan   +9 more
doaj   +1 more source

Molecular Detection of Alpha‐ and Betacoronaviruses in Bats from Afar Region, Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Bats are critical reservoirs of coronaviruses, yet gaps remain in understanding coronavirus diversity within bat populations in Eastern Ethiopia. A total of 141 bats were captured: 129 Chaerephon pumilus, 11 Epomophorus labiatus and 1 Mops condylurus. Coronaviruses detected in eight bats.
Bula Mengesha, Gebremedhin Romha, Gebremedhin Gebrezgabiher   +2 more
wiley   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

Advanced Science, Volume 13, Issue 24, 27 April 2026.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu, Hang Li, Peng Liu, Zhe Jiao, Ding Zhang, Zhelin Su, Sai Niu, Jintao Zhang, Yuejun Shi, Guiqing Peng   +9 more
wiley   +1 more source

Global Dynamics of Porcine Enteric Coronavirus PEDV Epidemiology, Evolution, and Transmission

Molecular Biology and Evolution, 2023
AbstractWith a possible origin from bats, the alphacoronavirus Porcine epidemic diarrhea virus (PEDV) causes significant hazards and widespread epidemics in the swine population. However, the ecology, evolution, and spread of PEDV are still unclear.
Zhang, Hao, Zou, Chuangchao, Peng, Ouyang, Ashraf, Usama, Xu, Qiuping, Gong, Lang, Fan, Baochao, Zhang, Yun, Xu, Zhichao, Xue, Chunyi, Wei, Xiaona, Zhou, Qingfeng, Tian, Xiaoyan, Shen, Hanqin, Li, Bin, Zhang, Xiangbin, Cao, Yongchang   +16 more
openaire   +2 more sources

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Emerging strains of porcine epidemic diarrhoea virus (PEDv) in Mexico [PDF]

Transboundary and Emerging Diseases, 2019
As an emerging disease, the porcine epidemic diarrhoea virus has caused substantial economic losses to the pork industry in Mexico, leading to piglet mortality rates of up to 100%. For detection, sequencing and genetic characterization of the virus, 68 samples of one-week-old piglets from pork farms in 17 states of Mexico were analysed.
Saúl Reveles‐Félix, Rosalba Carreón‐Nápoles, Susana Mendoza‐Elvira, Víctor Quintero‐Ramírez, Juvencio García‐Sánchez, Rebeca Martínez‐Bautista, Manuel Saavedra‐Montañez, Juan Joel Mosqueda Gualito, José Ivan Sánchez‐Betancourt   +8 more
openaire   +2 more sources

Proteomic and Metabolomic Profiling Elucidate the Impact of PEDV on Yorkshire Piglets and Reveal the Underlying Molecular Mechanism of PEDV Response

Agriculture, 2023
Porcine epidemic diarrhea virus (PEDV) is an RNA virus causing acute diarrhea, vomiting, dehydration and high mortality in piglets, and poses significant challenges for the global pig industry. However, the molecular mechanism underlying PEDV in piglets has not been well comprehended.
Lijun Shi, Huihui Li, Chunxiang Zhou, Lixian Wang   +3 more
openaire   +2 more sources