Results 51 to 60 of about 6,592 (133)

The Pseudotyped Replication-Deficient VSV with Spike from PEDV Induces Neutralizing Antibody Against PEDV

open access: yesVaccines
Background: Porcine epidemic diarrhea virus (PEDV) is a significant pathogen in swine, causing substantial economic losses worldwide. Despite the availability of existing vaccines, there is a critical need for novel vaccine platforms that ensure robust ...
Jingxuan Yi   +8 more
doaj   +1 more source

Transferrin receptor 1 levels at the cell surface influence the susceptibility of newborn piglets to PEDV infection.

open access: yesPLoS Pathogens, 2020
Porcine epidemic diarrhea virus (PEDV) mainly infects the intestinal epithelial cells of newborn piglets causing acute, severe atrophic enteritis. The underlying mechanisms of PEDV infection and the reasons why newborn piglets are more susceptible than ...
Shuai Zhang, Yanan Cao, Qian Yang
doaj   +1 more source

Applying Baculovirus Surface Display Technology for Influenza Cytokine Profiling, Serological Detection and Antiviral Screening

open access: yesMicrobial Biotechnology, Volume 19, Issue 6, June 2026.
By displaying the hemagglutinin (HA) or neuraminidase (NA) proteins of influenza viruses on the surface of baculoviruses and infected insect cells, a safe and flexible pseudovirus system capable of performing cytokine analysis, serological detection and antiviral drug screening is established.
Li‐Yun Cheng   +7 more
wiley   +1 more source

Molecular Detection of Alpha‐ and Betacoronaviruses in Bats from Afar Region, Ethiopia

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Bats are critical reservoirs of coronaviruses, yet gaps remain in understanding coronavirus diversity within bat populations in Eastern Ethiopia. A total of 141 bats were captured: 129 Chaerephon pumilus, 11 Epomophorus labiatus and 1 Mops condylurus. Coronaviruses detected in eight bats.
Bula Mengesha   +2 more
wiley   +1 more source

IFITM proteins are key entry factors for porcine epidemic diarrhea coronavirus

open access: yesJournal of Virology
Porcine epidemic diarrhea virus (PEDV) is a highly contagious coronavirus that poses a substantial threat to the global swine industry. However, our current understanding of the host factors crucial for PEDV infection remains limited.
Lilei Lv   +9 more
doaj   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

open access: yesAdvanced Science, Volume 13, Issue 24, 27 April 2026.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu   +9 more
wiley   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

open access: yesAdvanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras   +6 more
wiley   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

open access: yesAdvanced Science, Volume 13, Issue 11, 23 February 2026.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su   +15 more
wiley   +1 more source

No evidence of PEDV infection in French artificial insemination centers in 2015

open access: yesPorcine Health Management, 2019
Pigs infected by porcine epidemic diarrhea virus (PEDV) are affected by severe diarrhea, vomiting and dehydration. The severity of clinical signs depends on the virus strain.
S. Gallien   +6 more
doaj   +1 more source

Tailoring Advanced Metal‐Based Nanomedicines for Adaptable Nanodynamic Disease Therapies and Theranostics

open access: yesAdvanced Materials, Volume 38, Issue 1, 2 January 2026.
This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding   +11 more
wiley   +1 more source

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