Results 61 to 70 of about 10,162 (212)

Elimination of Porcine Epidemic Diarrhea Virus in an Animal Feed Manufacturing Facility [PDF]

, 2017
Citation: Huss AR, Schumacher LL, Cochrane RA, Poulsen E, Bai J, Woodworth JC, et al. (2017) Elimination of Porcine Epidemic Diarrhea Virus in an Animal Feed Manufacturing Facility. PLoS ONE 12(1): e0169612.
Bai, Jianfa, Cochrane, Roger A., Dritz, Steve S., Huss, Anne R., Jones, Cassandra K., Poulsen, Elizabeth, Schumacher, Loni L., Stark, Charles R., Woodworth, Jason C.   +8 more
core   +2 more sources

Stage of Gestation at Porcine Epidemic Diarrhea Virus Infection of Pregnant Swine Impacts Maternal Immunity and Lactogenic Immune Protection of Neonatal Suckling Piglets

Frontiers in Immunology, 2019
During pregnancy, the maternal immune response changes dramatically over the course of gestation. This has implications for generation of lactogenic immunity and subsequent protection in suckling neonates against enteric viral infections.
Stephanie N. Langel, Francine C. Paim, Moyasar A. Alhamo, Alexandra Buckley, Albert Van Geelen, Kelly M. Lager, Anastasia N. Vlasova, Linda J. Saif   +7 more
doaj   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, Volume 13, Issue 11, 23 February 2026.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Astragalus polysaccharide enhances maternal mucosal immunity against PEDV

mSphere
ABSTRACT Porcine epidemic diarrhea virus (PEDV), the major causative pathogen of porcine epidemic diarrhea, poses a severe threat to the swine industry, particularly affecting neonatal piglets. Maternal milk-derived IgA antibody is crucial for protecting piglets from PEDV infection.
Jianli Tang, Shuaiyong Wang, Jianmei Tang, Jinming Li   +3 more
openaire   +3 more sources

Completion of the Porcine Epidemic Diarrhoea Coronavirus (PEDV) Genome Sequence [PDF]

Virus Genes, 2001
The sequence of the replicase gene of porcine epidemic diarrhoea virus (PEDV) has been determined. This completes the sequence of the entire genome of strain CV777, which was found to be 28,033 nucleotides (nt) in length (excluding the poly A-tail). A cloning strategy, which involves primers based on conserved regions in the predicted ORF1 products ...
Kocherhans, Rolf, Bridgen, Anne, Ackermann, Mathias, Tobler, Kurt   +3 more
openaire   +2 more sources

IFITM proteins are key entry factors for porcine epidemic diarrhea coronavirus

Journal of Virology
Porcine epidemic diarrhea virus (PEDV) is a highly contagious coronavirus that poses a substantial threat to the global swine industry. However, our current understanding of the host factors crucial for PEDV infection remains limited.
Lilei Lv, Huaye Luo, Jingxuan Yi, Kang Zhang, Yanhua Li, Wu Tong, Yifeng Jiang, Yanjun Zhou, Guangzhi Tong, Changlong Liu   +9 more
doaj   +1 more source

Tailoring Advanced Metal‐Based Nanomedicines for Adaptable Nanodynamic Disease Therapies and Theranostics

Advanced Materials, Volume 38, Issue 1, 2 January 2026.
This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding, Wenhao Li, Ling Mei, Suling Luo, Jing Tao, Chongxiu Shi, Hongping Yang, Wei Feng, Yungchang Chen, Yu Chen, Jong Seung Kim, Xue Shen   +11 more
wiley   +1 more source

Transferrin receptor 1 levels at the cell surface influence the susceptibility of newborn piglets to PEDV infection.

PLoS Pathogens, 2020
Porcine epidemic diarrhea virus (PEDV) mainly infects the intestinal epithelial cells of newborn piglets causing acute, severe atrophic enteritis. The underlying mechanisms of PEDV infection and the reasons why newborn piglets are more susceptible than ...
Shuai Zhang, Yanan Cao, Qian Yang
doaj   +1 more source

Transcriptome Analysis of LLC-PK Cells Single or Coinfected with Porcine Epidemic Diarrhea Virus and Porcine Deltacoronavirus

Viruses, 2023
Porcine epidemic diarrhea virus (PEDV) and porcine deltacoronavirus (PDCoV) are the two most prevalent swine enteric coronaviruses worldwide. They commonly cause natural coinfections, which worsen as the disease progresses and cause increased mortality ...
Yanzhen Lu, Ruiming Yu, Lixin Tong, Liping Zhang, Zhongwang Zhang, Li Pan, Yonglu Wang, Huichen Guo, Yonghao Hu, Xinsheng Liu   +9 more
doaj   +1 more source

Heat shock protein 70 could enhance porcine epidemic diarrhoea virus replication by interacting with membrane proteins

Veterinary Research, 2021
In this study, we investigated the role of heat shock protein 70 (HSP70) in porcine epidemic diarrhoea virus (PEDV) replication. We found that PEDV infection induced strong HSP70 overexpression in the very early stage of infection. We also confirmed that
Jae-Yeon Park, Jihoon Ryu, Jung-Eun Park, Eui-Ju Hong, Hyun-Jin Shin   +4 more
doaj   +1 more source