Results 71 to 80 of about 994,354 (266)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

ReviewFlow: Intelligent Scaffolding to Support Academic Peer Reviewing [PDF]

open access: yes
Peer review is a cornerstone of science. Research communities conduct peer reviews to assess contributions and to improve the overall quality of science work. Every year, new community members are recruited as peer reviewers for the first time. How could technology help novices adhere to their community's practices and standards for peer reviewing?
arxiv   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

Correlation Between Helicobacter pylori Infection and Tongue Manifestations: A Meta-analysis

open access: yesDigital Chinese Medicine, 2018
: Objective To analyze the relationship between Helicobacter pylori (H. pylori) infection and the manifestations of the tongue.Methods Without language restrictions, we searched databases including CAJD, CBMdisc, CDFD, CMFD, PubMed, Cochrane, and EMBASE ...
Bo-Nan HOU   +6 more
doaj  

Aggregating post-publication peer reviews and ratings

open access: yesFrontiers in Computational Neuroscience, 2012
Allocating funding for research often entails the review of the publications authored by a scientist or a group of scientists. For practical reasons, in many cases this review cannot be performed by a sufficient number of specialists in the core domain ...
Răzvan Valentin Florian
doaj   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Efficacy of a meal sequence in patients with type 2 diabetes: a systematic review and meta-analysis

open access: yesBMJ Open Diabetes Research & Care, 2022
Yuki Kataoka   +3 more
doaj   +1 more source

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