Results 71 to 80 of about 3,030,229 (330)
Digital Chinese Medicine, 2018 : Stroke is the leading cause of human disability with limited effective drugs availability. The disruption of multiple signaling pathways in stroke makes developing new drugs be difficult.
Jian-Gang SHEN
doaj
Rethinking Resource Allocation in Science
, 2019 US funding agencies alone distribute a yearly total of roughly $65B dollars largely through the process of proposal peer review: scientists compete for project funding by submitting grant proposals which are evaluated by selected panels of peer reviewers.
Bollen, Johan +3 more
core +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
Journal of Medicine & Health, 2017 We would like to thank our peer reviewers for the precious contributions in providing clinical, scientific, and methodological expertise for JMH Volume 2 Number 2 August 2018. We appreciate every thoughtful review of submitted manuscripts and for making important contributions to improve the scientific quality of articles published in JMH.
openaire +4 more sources
PeerPigeon: A Web Application to Support Generalised Peer Review
, 2008 Peer Review (also known as Peer Assessment) is an important technique in learning, but can be difficult to support through e-learning due to the complexity and variety of peer review processes.
Millard, David +2 more
core
Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase
FEBS Letters, EarlyView.The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu +5 more
wiley +1 more source
FEBS Letters, EarlyView.The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff +4 more
wiley +1 more source
Digital Chinese Medicine Research: an Overview
Digital Chinese Medicine, 2018 : Digital Chinese medicine (DCM) is an emerging interdisciplinary field developed from traditional Chinese medicine (TCM) and information science. In this article, we consider the significance and propose an architecture for DCM research, and highlight ...
Hui-Yong Huang, Jun-Feng Yan, Zhi-Xi Hu
doaj
Peer review - Why, when and how
International Journal of Cardiology Congenital Heart Disease, 2021 Peer review has a key role in ensuring that information published in scientific journals is as truthful, valid and accurate as possible. It relies on the willingness of researchers to give of their valuable time to assess submitted papers, not just to ...
Philip J. Steer, Sabine Ernst
doaj
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source