Results 131 to 140 of about 33,392 (283)

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

open access: yesBMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang   +7 more
wiley   +1 more source

Data from Increasing the Antitumor Effect of an EpCAM-Targeting Fusion Toxin by Facile Click PEGylation

open access: gold, 2023
Manuel Simon   +4 more
openalex   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

open access: yesBMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou   +6 more
wiley   +1 more source

One‐Stone‐Two‐Birds Carrier‐Free Nano‐Cocktail Enables Synergistic Eradication of Cancer Cells/Stem Cells in Breast Cancer Treatment

open access: yesExploration, EarlyView.
ABSTRACT Cancer stem cells (CSCs) are widely recognized as the culprits of chemoresistance, tumor metastasis, and relapse. Moreover, most chemotherapeutic drugs not only fail to eliminate CSCs effectively, but also induce the acquisition of stemness characteristics in non‐stem cancer cells. Herein, we propose a cancer cells/CSCs double‐killing modality
Tongyao Zhao   +10 more
wiley   +1 more source

Development and in vitro evaluation of chitosan nanoparticles encapsulating Phoenix dactylifera L. (Ajwah) seed extract with supporting in silico molecular docking analysis

open access: yesFood Biomacromolecules, EarlyView.
Abstract This research describes the engineering of chitosan nanoparticles (CS NPs) via ionic gelation to I'm double or somethingencapsulate Ajwah seed extract (ASE), repurposing a plant waste product for its documented antioxidant and anticancer potential.
Jailan E. Elhalawani   +2 more
wiley   +1 more source

Paclitaxel-Loaded, Pegylated Carboxylic Graphene Oxide with High Colloidal Stability, Sustained, pH-Responsive Release and Strong Anticancer Effects on Lung Cancer A549 Cell Line

open access: yesPharmaceutics
Background: Graphene Oxide (GO) has shown great potential in biomedical applications for cancer therapeutics. The biosafety and stability issues of GO in biological media have been addressed by functionalization with polyethylene glycol (PEG).
Athina Angelopoulou   +6 more
doaj   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

open access: yesIbrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma   +3 more
wiley   +1 more source

Optimum Preparation Method for Self-Assembled PEGylation Nano-Adjuvant Based on Rehmannia glutinosa Polysaccharide and Its Immunological Effect on Macrophages

open access: yesInternational Journal of Nanomedicine, 2019
Yee Huang,1 Li Nan,1,2 Chenwen Xiao,1 Quanan Ji,1 Ke Li,1 Qiang Wei,1 Yan Liu,1 Guolian Bao1 1Institute of Animal Husbandry and Veterinary Medicine, Zhejiang Academy of Agricultural Science, Hangzhou 310021, People’s Republic of China; 2Zhejiang ...
Huang Y   +7 more
doaj  

Relieving PEGylation [PDF]

open access: yesNature Chemistry, 2011
Matthew C. Parrott, Joseph M. DeSimone
openaire   +1 more source

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