Results 41 to 50 of about 33,392 (283)

Er:Y₂O₃ and Nd:Y₂O₃ Nanoparticles: Synthesis, Pegylation, Characterization and Study of Their Luminescence Properties

Chemosensors, 2022
Lanthanide-doped yttrium oxide nanoparticles can display selective upconversion properties, rendering them invaluable in the field of nanomedicine for both sensing and diagnostics.
Regina Maria Chiechio, Rosalia Battaglia, Angela Caponnetto, Ester Butera, Giorgia Franzò, Riccardo Reitano, Michele Purrello, Marco Ragusa, Davide Barbagallo, Cristina Barbagallo, Cinzia Di Pietro, Valérie Marchi, Maria José Lo Faro, Annalinda Contino, Giuseppe Maccarrone, Paolo Musumeci   +15 more
doaj   +1 more source

Long acting growth hormone (LAGH), an update

Frontiers in Pediatrics, 2023
In 1957, Maurice Raben at Yale was able to isolate and purify growth hormone from cadaveric pituitary glands. Pituitary growth hormone was the only way to treat children with growth hormone (GH) deficiency, until 1985 when recombinant GH became available
Margaret Steiner Grillo, Jacklyn Frank, Paul Saenger   +2 more
doaj   +1 more source

Nanoparticles in the treatment of chronic lung diseases [PDF]

, 2019
Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G, Cosnarovici, Maria, Negrean, Vasile, Orasan, Olga H, Para, Ioana, Perne, Mirela G, Popovici, Ionela, Ruta, Victoria M, Tarmure, Simina, Todea, Doina A   +9 more
core   +2 more sources

PEGylated Systems in Pharmaceutics [PDF]

Polymer Science, Series C, 2020
This review addresses the use of poly(ethylene glycol) (PEG) and PEG conjugation for the design of novel dosage forms and the modification of biomolecules. The peculiarities of PEGylated nanoparticles, liposomes, proteins, enzymes, and small drug and polyelectrolyte molecules and their influence on systemic drug delivery, including overcoming of ...
Porfiryeva, N. N., Moustafine, R. I., Khutoryanskiy, V. V.   +2 more
openaire   +1 more source

Design of New Polyaspartamide Copolymers for siRNA Delivery in Antiasthmatic Therapy

Pharmaceutics, 2020
Here, a novel protonable copolymer was realized for the production of polyplexes with a siRNA (inhibitor of STAT6 expression in asthma), with the aim of a pulmonary administration.
Emanuela Fabiola Craparo, Salvatore Emanuele Drago, Nicolò Mauro, Gaetano Giammona, Gennara Cavallaro   +4 more
doaj   +1 more source

DEVELOPMENT OF OPTIMAL EXPERIMENTAL THERAPEUTIC REGIMENS ADMINISTRATION OF IMMOBILIZED INTERFERON α-2b

Бюллетень сибирской медицины, 2014
The development of optimal experimental therapeutic schemes of immobilized interferon α-2b (production of JSC «Siberian Center for Pharmacology and Biotechnology», Novosibirsk) administration was conducted in the frame of the common program of pre ...
O. G. Shitikova, E. Yu. Sherstoboev, N. V. Masnaya, M. G. Danilets, E. S. Trofimova, A. A. Ligacheva, P. G. Madonov, D. N. Kinsht, K. I. Ershov, M. A. Shilova   +9 more
doaj   +1 more source

Nucleic Acid Carriers Based on Precise Polymer Conjugates [PDF]

, 2011
Polymer polydispersity, random conjugation of functional groups, and poorly understood structure–activity relationships have constantly hampered progress in the development of nucleic acid carriers.
Troiber, Christina, Wagner, Ernst
core   +1 more source

Pharmacokinetic Consequences of Pegylation [PDF]

Drug Delivery, 2006
Pegylation, generally described as the molecular attachment of polyethylene glycols (PEGs) with different molecular weights to active drug molecules or surface treatment of drug-bearing particles with PEGs, is one of the most promising and extensively studied strategies with the goal of improving the pharmacokinetic behavior of the therapeutic drugs. A
Mehrdad, Hamidi, Amir, Azadi, Pedram, Rafiei   +2 more
openaire   +2 more sources

Simple Syntheses of New Pegylated Trehalose Derivatives as a Chemical Tool for Potential Evaluation of Cryoprotectant Effects on Cell Membrane

Molecules, 2020
In our work, we developed the synthesis of new polyfunctional pegylated trehalose derivatives and evaluated their cryoprotective effect using flow cytometry.
Karel Pomeisl, Jan Richter, Martin Golan, Irena Kratochvílová   +3 more
doaj   +1 more source

PEGylation of the antimicrobial peptide LyeTx I-b maintains structure-related biological properties and improves selectivity

Frontiers in Molecular Biosciences, 2022
The biological activity of antimicrobial peptides and proteins is closely related to their structural aspects and is sensitive to certain post-translational modifications such as glycosylation, lipidation and PEGylation.
Júlio César Moreira Brito, Lucas Raposo Carvalho, Amanda Neves de Souza, Guilherme Carneiro, Paula Prazeres Magalhães, Luiz Macêdo Farias, Natália Rocha Guimarães, Rodrigo Moreira Verly, Jarbas Magalhães Resende, Maria Elena de Lima   +9 more
doaj   +1 more source