Results 41 to 50 of about 165,634 (303)

Proof of concept for the clinical effects of oral rilzabrutinib, the first Bruton tyrosine kinase inhibitor for pemphigus vulgaris: the phase II BELIEVE study

British Journal of Dermatology, 2021
Bruton tyrosine kinase (BTK) inhibition targets B‐cell and other non‐T‐cell immune cells implicated in the pathophysiology of pemphigus, an autoimmune disease driven by anti‐desmoglein autoantibodies.
D. Murrell, A. Patsatsi, P. Stavropoulos, S. Baum, T. Zeeli, J. Kern, A. Roussaki-Schulze, R. Sinclair, I. Bassukas, D. Thomas, A. Neale, P. Arora, F. Caux, V. Werth, S. Gourlay, P. Joly   +15 more
semanticscholar   +1 more source

Validation study of bullous pemphigoid and pemphigus vulgaris recording in routinely collected electronic primary healthcare records in England

BMJ Open, 2020
Objectives The validity of bullous pemphigoid and pemphigus vulgaris recording in routinely collected healthcare data in the UK is unknown. We assessed the positive predictive value (PPV) for bullous pemphigoid and pemphigus vulgaris primary care Read ...
Yana Vinogradova, Julia Hippisley-Cox, Sonia Gran, Sinéad M Langan, Monica S M Persson, Karen E Harman, Kim S Thomas   +6 more
doaj   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Post-Pemphigus Acanthomata Presenting as an Isolated, Hyperkeratotic Plaque

Dermatopathology, 2023
Post-pemphigus acanthomas have been rarely discussed in the literature. A prior case series identified 47 cases of pemphigus vulgaris and 5 cases of pemphigus foliaceus, out of which 13 developed acanthomata as a part of the healing process. Additionally,
Rachita Pandya, Yanjia Zhou, Mansee Desai, Nancy Anderson, Ashley Elsensohn   +4 more
doaj   +1 more source

Mucosal-dominant pemphigus vulgaris in a captopril-taking woman with angioedema [PDF]

Anais Brasileiros de Dermatologia, 2015
We describe a 39-year-old woman with an apparent captopril-induced, contact mucosal-dominant pemphigus vulgaris and angioedema, who took captopril during a bout of arterial hypertension.
Justyna Gornowicz-Porowska, Marian Dmochowski, Pawel Pietkiewicz, Monika Bowszyc-Dmochowska   +3 more
doaj   +2 more sources

Relationship Between Pemphigus Vulgaris Severity and PCR-positive Herpes Simplex Virus

Acta Dermato-Venereologica, 2022
Pemphigus vulgaris is a rare autoimmune skin disease. Although herpes simplex virus has been associated with autoimmune diseases, evidence regarding its association with pemphigus vulgaris exacerbations is scarce. This retrospective cohort study aimed to
Sharon Baum, Itai Atar, Dan Coster, Sara Dovrat, Michal Solomon, Eli Sprecher, Tal Zeeli, Aviv Barzilai   +7 more
doaj   +1 more source

S2k guidelines for the treatment of pemphigus vulgaris/foliaceus and bullous pemphigoid: 2019 update

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2020
(1) Department of Dermatology, University of Lübeck, Lübeck, Germany (2) Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany (3) Department of Dermatology, University Hospital Erlangen, Erlangen, Germany (4) Department of ...
Enno Schmidt, M. Sticherling, Miklós Sárdy, Rüdiger Eming, Matthias Goebeler, M. Hertl, Silke C. Hofmann, N. Hunzelmann, Johannes S. Kern, Harald Kramer, A. Nast, Hans‐Dieter Orzechowski, Christiane Pfeiffer, Volker Schuster, C. Sitaru, M. Zidane, D. Zillikens, M. Worm   +17 more
semanticscholar   +1 more source

Pemphigus vulgaris and focal segmental glomerulosclerosis (FSGS): First reported case and a review of the literature

Clinical Case Reports, 2023
Key Clinical Message There may be a connection between pemphigus vulgaris and nephrotic syndrome, as evidenced by the occurrence of focal segmental glomerulosclerosis in our pemphigus vulgaris patient and reviewing relevant literature.
Afsaneh Sadeghzadeh‐Bazargan, Atefeh Amouzegar, Maryam Abolhasani, Abbas Dehghani, Azadeh Goodarzi, Seyyedeh Tahereh Rahimi   +5 more
doaj   +1 more source

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]

, 2016
Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir, Banning, Antje, Eming, Rüdiger, Exner, Yvonne, Hertl, Michael, Kurrle, Nina, Tikkanen, Ritva, Völlner, Frauke   +7 more
core   +1 more source

Analysis of the reactivity of indirect immunofluorescence in patients with pemphigus foliaceus and pemphigus vulgaris using rat bladder epithelium as a substrate

Clinics, 2011
OBJECTIVES: To evaluate the reactivity of indirect immunofluorescence using rat bladder epithelium as a substrate in patients with pemphigus foliaceus and pemphigus vulgaris from the Department of Dermatology, University of São Paulo Medical School ...
Damaris G. Ortolan, Danielle P. G. Souza, Valéria Aoki, Claudia G. Santi, Tatiana V. B. Gabbi, Ligia M. F. Ichimura, Celina W. Maruta   +6 more
doaj   +1 more source