Results 41 to 50 of about 5,901 (191)

Wide-targeted gene expression infers tissue-specific molecular signatures of lipid metabolism in fed and fasted fish [PDF]

, 2017
European sea bass (Dicentrarchus labrax) is one of the most important species for Mediterranean aquaculture. It is therefore crucial to establish appropriate feeding management regimens and to gain better knowledge of nutritional requirements for this ...
Benedito-Palos, Laura, Pérez-Sánchez, Jaume, Rimoldi, S., Terova, G.   +3 more
core   +1 more source

JLP/Foxk1/N-cadherin axis fosters a partial epithelial-mesenchymal transition state in epithelial tubular cells

iScience, 2023
Summary: Renal tubular epithelial cells (TECs) undergoing partial epithelial-mesenchymal transition (pEMT) during renal fibrosis has been recognized as a featuring and detrimental event.
Maoqing Tian, Lu Zhang, Meng Zhang, Liwen Qiao, Bingqing Xu, Chen Li, Shan Liu, Yuan Song, Zhongping Wei, Yujuan Wang, Huiming Wang   +10 more
doaj   +1 more source

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice. [PDF]

, 2015
Increased consumption of folic acid is prevalent, leading to concerns about negative consequences. The effects of folic acid on the liver, the primary organ for folate metabolism, are largely unknown.
Best, A, Caudill, MA, Christensen, KE, Deng, L, Greene, ND, Leung, KY, Lévesque, N, Malysheva, OV, Mikael, LG, Rozen, R, Wu, Q   +10 more
core   +1 more source

Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q

Redox Biology, 2021
Mitochondrial energy production and function rely on optimal concentrations of the essential redox-active lipid, coenzyme Q (CoQ). CoQ deficiency results in mitochondrial dysfunction associated with increased mitochondrial oxidative stress and a range of
Anita Ayer, Daniel J. Fazakerley, Cacang Suarna, Ghassan J. Maghzal, Diba Sheipouri, Kevin J. Lee, Michelle C. Bradley, Lucía Fernández-del-Rio, Sergey Tumanov, Stephanie MY. Kong, Jelske N. van der Veen, Andrian Yang, Joshua W.K. Ho, Steven G. Clarke, David E. James, Ian W. Dawes, Dennis E. Vance, Catherine F. Clarke, René L. Jacobs, Roland Stocker   +19 more
doaj   +1 more source

Nanoparticle-based delivery enhances anti-inflammatory effect of low molecular weight heparin in experimental ulcerative colitis

Drug Delivery, 2017
Epithelial administration of low molecular weight heparin (LMWH) has proven its therapeutic efficiency in ulcerative colitis (UC) but still lacks of a sufficiently selective drug delivery system. Polymeric nanoparticles were used here not only to protect
Tawfek Yazeji, Brice Moulari, Arnaud Beduneau, Valentin Stein, Dirk Dietrich, Yann Pellequer, Alf Lamprecht   +6 more
doaj   +1 more source

Energy–Momentum Pseudotensor and Superpotential for Generally Covariant Theories of Gravity of General Form

Universe, 2020
The current paper is devoted to the investigation of the general form of the energy–momentum pseudotensor (pEMT) and the corresponding superpotential for the wide class of theories.
Roman Ilin, Sergey Paston
doaj   +1 more source

The Role of Phosphatidylethanolamine-N-methyltransferase (PEMT) Gene rs12449964 Polymorphism in the Development of Acute Pancreatitis and its Complications

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2019
Background. Acute pancreatitis is considered to be an important issue in modern medicine. The phosphatidylethanolamine-N-methyltransferase enzyme plays a significant role in the regulation of lipid metabolism by catalyzing the process of methylation of ...
T. A. Samgina, Yu. E. Azarova, Yu. V. Kanishchev, V. A. Lazarenko, P. M. Nazarenko, A. V. Polonikov   +5 more
doaj   +1 more source

Replication and exploratory analysis of 24 candidate risk polymorphisms for neural tube defects. [PDF]

, 2014
BackgroundNeural tube defects (NTDs), which are among the most common congenital malformations, are influenced by environmental and genetic factors. Low maternal folate is the strongest known contributing factor, making variants in genes in the folate ...
Abaan, Hatice Ozel, Brody, Lawrence C, Browne, Marilyn L, Caggana, Michele, Kay, Denise M, Kirke, Peadar N, McGrath, Emily C, Mills, James L, Molloy, Anne M, Pangilinan, Faith, Parle-McDermott, Anne, Scott, John M, Shane, Barry, Sutton, Marie, Troendle, James F   +14 more
core   +3 more sources

New Insights Into the Role and Mechanism of Partial Epithelial-Mesenchymal Transition in Kidney Fibrosis

Frontiers in Physiology, 2020
Epithelial-mesenchymal transition (EMT) is described as the process in which injured renal tubular epithelial cells undergo a phenotype change, acquiring mesenchymal characteristics and morphing into fibroblasts.
Lili Sheng, Shougang Zhuang, Shougang Zhuang   +2 more
doaj   +1 more source

Interplay between Partial EMT and Cisplatin Resistance as the Drivers for Recurrence in HNSCC

Biomedicines, 2022
This study aims to investigate the role of partial epithelial to mesenchymal transition (pEMT)-related proteins in modulating Cisplatin resistance in head and neck squamous cell carcinoma (HNSCC).
Julia Ingruber, Jozsef Dudas, Susanne Sprung, Bianca Lungu, Felicitas Mungenast   +4 more
doaj   +1 more source