Results 41 to 50 of about 27,456 (253)

A scoping review of disease‐modifying antirheumatic drug nonadherence in rheumatoid arthritis: Measurement, prevalence and implications for clinical practice

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Adherence to disease‐modifying antirheumatic drugs (DMARDs) has been associated with improved treatment outcomes, but how adherence is reported ranges between studies. We therefore aimed to determine how nonadherence to DMARDs used to treat rheumatoid arthritis (RA) has been measured and to report the nonadherence rate with each measure identified.
Lauren Fraser   +7 more
wiley   +1 more source

COMPARATIVE OF NATURAL ZEOLITE – CLINOPTILOLITE ELIMINATION OF METAL IONS/ESPECIALLY Cu (II) WITH D-PENICILLAMINE FROM BIOLOGICAL ENVIRONMENTS

open access: yesRudarsko-geološko-naftni Zbornik, 2021
Clinoptilolite is used as an adsorbent to remove heavy metal cations due to its function as a molecular sieve. This molecular sieve characteristic has made it possible to study the efficiency of clinoptilolite and D-Penicillamine in a comparative way in ...
Abdollah Forughirad   +4 more
doaj  

Chiral Imprinting on Inorganic Nanoparticles for Enantioselective Surface Recognition

open access: yesSmall, EarlyView.
Chiral imprinting on titanium dioxide (TiO2) nanoparticles is achieved by introducing a chiral ligand during nucleation and growth. After ligand removal by ultraviolet (UV) irradiation, enantioselectivity is demonstrated via refunctionalization in a racemic mixture, where the surface preferentially binds the original enantiomer. These results show that
Susanna Tinello   +2 more
wiley   +1 more source

Validity of D-penicillamine in experimental cerebral vasospasm therapy

open access: yesInterdisciplinary Neurosurgery
Background: Cerebral vasospasm is a reversible vessel constriction following subarachnoid hemorrhage. Immunoreactive and inflammatory mechanisms induce long-term vasoconstriction and vessel dilatation inhibition.
Ersin Haciyakupoglu   +6 more
doaj   +1 more source

Penicillamine as radiation protector against gamma radiation effect on complete blood count parameters of guinea pigs

open access: yesAl-Azhar Assiut Medical Journal, 2019
Background and aim The increasing use of nuclear technology has increased the risk of exposure to radiation. Exposure to radiation induces harms to human beings. The blood and blood-forming organs are one of the most sensitive to radiation.
Yasser M.M El-Dessouky   +2 more
doaj   +1 more source

Inhibitory effect of D-penicillamine stabilized silver cluster on Escherichia coli and Staphylococcus aureus

open access: yesZhongguo gonggong weisheng, 2022
Objective To observe inhibitory effect of silver cluster assemblies capped by D-penicillamine on Escherichia coli (E.coli) and Staphylococcus aureus (S.aureus).
Yi HAN, Ling-can KONG, Geng-wei LI
doaj   +1 more source

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley   +1 more source

Metal‐Responsive Up‐Regulation of Bifunctional Disulfides for Suppressing Protein Misfolding and Promoting Oxidative Folding

open access: yesAngewandte Chemie, Volume 137, Issue 36, September 1, 2025.
A stress‐responsive folding promotor was developed by conjugating metal‐binding ligands and a redox‐active disulfide. The oxidative strength of the bifunctional disulfide was enhanced by metal coordination, inhibiting protein misfolding and up‐regulating the oxidative folding capacity under metal stress.
Keita Mori   +8 more
wiley   +2 more sources

Crystal structure of S,N-dibenzyl-d-penicillamine monohydrate

open access: yesActa Crystallographica Section E, 2014
In the asymmetric unit of the title compound, C19H23NO2S·H2O, there are two independent organic molecules and two water molecules. Both organic molecules exist as the zwitterionic form.
Nobuto Yoshinari, Takumi Konno
doaj   +1 more source

Methanobactin rapidly facilitates biliary copper excretion in a Wilson disease rat model visualised by 64Cu PET/MRI

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Methanobactins are peptides with high copper affinity and potential to treat Wilson disease. We examined how two methanobactins (ARBM101 and MB‐OB3b) affected copper handling in the LPP Atp7b−/− Wilson disease rat model, compared to penicillamine or saline, by 64Cu positron emission tomography/magnetic resonance imaging ...
Emilie Munk Lynderup   +11 more
wiley   +1 more source

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