Results 31 to 40 of about 460,006 (298)
Novel Penicillin Analogues as Potential Antimicrobial Agents; Design, Synthesis and Docking Studies. [PDF]
PLoS ONE, 2015 A number of penicillin derivatives (4a-h) were synthesized by the condensation of 6-amino penicillinic acid (6-APA) with non-steroidal anti-inflammatory drugs as antimicrobial agents.
Zaman Ashraf +3 more
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Construction and Activity Testing of a Modular Fusion Peptide against Enterococcus faecalis
Antibiotics, 2023 The emergence of antibiotic resistance in enterococci is a great concern encountered worldwide. Almost all enterococci exhibit significant levels of resistance to penicillin, ampicillin, semi-synthetic penicillin and most cephalosporins, primarily due to
Salim Manoharadas +4 more
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Penicillin-Binding Proteins in Leptospira interrogans [PDF]
Antimicrobial Agents and Chemotherapy, 2001 ABSTRACT The Leptospira interrogans ponA and pbpB genes were isolated and characterized. ponA and pbpB encode the penicillin-binding proteins (PBPs) 1 and 3, respectively.
Brenot, A +3 more
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Frontiers in Microbiology, 2022 Streptococcus pneumoniae is a common human pathogen that can cause severe invasive pneumococcal diseases (IPDs). Penicillin-binding proteins (PBPs) are the targets for β-lactam antibiotics (BLAs), which are the common empirical drugs for treatment of ...
Menglan Zhou +11 more
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Molecular docking of human serum albumin with penicillin G determinants
Біофізичний вісник, 2023 Background: Human serum albumin (HSA) is the main pharmacokinetic effector of many medications, including penicillin G and its metabolites. An urgent problem of practical medicine is immediate hypersensitivity reactions caused by penicillin toxicity ...
N. V. Khmil, V. G. Kolesnikov
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Penicillin-binding proteins in Clostridium perfringens [PDF]
Antimicrobial Agents and Chemotherapy, 1981 The penicillin-binding proteins (PBPs) of Clostridium perfringens were studied. Six PBPs ranging in molecular weight from approximately 42,000 to 100,000 were detected in the cytoplasmic membrane. The relative affinities of the PBPs for 16 beta-lactam antibiotics were determined.
T F, Murphy, M, Barza, J T, Park
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Crystals, 2016 In spite of the enormous biological and clinical significance of penicillin-binding protein (PBP)/β-lactamase (βL), few of their many homologs (PBP)/βLs homologs) have been studied crystallographically, and have known functions.
Bum Han Ryu +4 more
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On Column Binding a Real-Time Biosensor for β-lactam Antibiotics Quantification
Molecules, 2020 This work aimed to develop accurate, quick, and practical tools for the detection of residues of penicillin G antibiotic in biological and non-biological samples.
Shahla M. Abdullah, Shwan Rachid
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The penicillin binding proteins of the genus Haemophilus [PDF]
Journal of Medical Microbiology, 1988 We questioned whether the penicillin binding protein (PBP) profiles of representative strains from the 19 species varied within the genus Haemophilus and whether these profiles would be of taxonomic value. Seventeen of the 19 representative strains studied had distinct PBP profiles; only those of H. avium and H. paragallinarum were identical.
P M, Mendelman, D A, Serfass
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Gut Pathogens, 2021 Background Amoxicillin-resistant H. pylori strains are increasing worldwide. To explore the potential resistance mechanisms involved, the 3D structure modeling and access tunnel prediction for penicillin-binding proteins (PBP1A) was performed, based on ...
Bahareh Attaran +7 more
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