Detection of pbp2b and ermB genes in clinical isolates of Streptococcus pneumoniae
Background: Streptococcus pneumoniae is a major human pathogen. The emergence of penicillin resistant strains since the 1970s has been life threatening and the evolution of the bacteria have enabled itself to develop resistance to many other antibiotics ...
Navindra Kumari +2 more
doaj +1 more source
Nanoantibiotics: Functions and Properties at the Nanoscale to Combat Antibiotic Resistance
One primary mechanism for bacteria developing resistance is frequent exposure to antibiotics. Nanoantibiotics (nAbts) is one of the strategies being explored to counteract the surge of antibiotic resistant bacteria.
M. Mustafa Mamun +3 more
doaj +1 more source
Case Report: Not All Neurological Symptoms Respond Well to Penicillin in Patients With Neurosyphilis
Patients with neurosyphilis present with a wide range of neurological symptoms, the response of which to penicillin is not well known. In this paper, we analyzed the clinical video-electroencephalogram (EEG) features of neurosyphilis in a 54-year-old man
Xiaoli Wang +4 more
doaj +1 more source
Acute Rheumatic Fever: Where Do We Stand? An Epidemiological Study in Northern Italy
Acute rheumatic fever (ARF) is a non-septic complication of group A β-hemolytic streptococcal (GAS) throat infection. Since 1944, ARF diagnosis relies on the Jones criteria, which were periodically revised.
Achille Marino +15 more
doaj +1 more source
The Impact of a Reported Penicillin Allergy on Surgical Site Infection Risk
Background A reported penicillin allergy may compromise receipt of recommended antibiotic prophylaxis intended to prevent surgical site infections (SSIs). Most patients with a reported penicillin allergy are not allergic.
K. Blumenthal +5 more
semanticscholar +1 more source
Cephalosporin Induced Toxic Epidermal Necrolysis and Subsequent Penicillin Drug Exanthem
Background: Drug hypersensitivity is classically divided into IgE mediated and non-IgE mediated disease. We report a rare case of consequent IgE mediated and non-IgE mediated reactions within the beta lactam class of antibiotics. Case Summary: An 84-year-
Amanda Lam +2 more
doaj +1 more source
The peptidoglycan cell wall is essential for the survival and morphogenesis of bacteria1. For decades, it was thought that only class A penicillin-binding proteins (PBPs) and related enzymes effected peptidoglycan synthesis.
A. Taguchi +8 more
semanticscholar +1 more source
The Discovery of Penicillin—New Insights After More Than 75 Years of Clinical Use
After just over 75 years of penicillin’s clinical use, the world can see that its impact was immediate and profound. In 1928, a chance event in Alexander Fleming’s London laboratory changed the course of medicine.
R. Gaynes
semanticscholar +1 more source
PRINCIPLES OF ANTIBIOTIC TREATMENT OF OUT-OF-HOSPITAL UPPER RESPIRATORY TRACT INFECTIONS IN CHILDREN
Special features of etiology of respiratory tract bacterial infections in children in depending of localization of involvement are analyzed in this study. In the article the main principles of rational antibacterial therapy of infectious and inflammatory
A. L. Zaplatnikov +3 more
doaj +1 more source
Differences in beta-lactam and penicillin allergy: Beyond the West and focusing on Asia-Pacific
Beta-lactam (BL) antibiotic “allergy” labels are common, but often overdiagnosed. Although much research has been focused on the BL allergy and the delabelling process in the West, studies from other parts of the world remain sparse. This review outlines
Hugo W.F. Mak +4 more
doaj +1 more source

