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OBJETIVO: Apresentar uma abordagem prática ao diagnóstico e conduta na alergia a antibióticos beta-lactâmicos. FONTES DOS DADOS: Periódicos da área de alergia indexados nas bases MEDLINE e LILACS, além de estudos e textos clássicos que tratam do tema ...
Nelson A. Rosário+1 more
doaj +1 more source
A new crystal form of penicillin acylase from Escherichia coli [PDF]
A new crystal form of penicillin acylase (penicillin amidohydrolase, E.C. 3.5.1.11) from Escherichia coli W (ATCC 11105) is reported. The crystals were grown using a combination of hanging-drop and streak-seeding methods.
Brannigan, J.A.+4 more
core +2 more sources
Introduction of 13-valent pneumococcal conjugate vaccine in the United States was not associated with a significant change in prevalence of penicillin resistance in nonvaccine type serotypes because of the variable success of highly resistant serotypes ...
Cheryl P. Andam+5 more
doaj +1 more source
Antibiotic resistance in the environment, with particular reference to MRSA [PDF]
The introduction of β-lactam antibiotics (penicillins and cephalosporins) in the 1940s and 1950s probably represents the most dramatic event in the battle against infection in human medicine.
Aarestrup+171 more
core +1 more source
The Discovery of Penicillin—New Insights After More Than 75 Years of Clinical Use
After just over 75 years of penicillin’s clinical use, the world can see that its impact was immediate and profound. In 1928, a chance event in Alexander Fleming’s London laboratory changed the course of medicine.
R. Gaynes
semanticscholar +1 more source
We report the results of a computational study of TiO2 nanoclusters of various sizes as well as of complex systems with various molecules adsorbed onto the clusters to set the ground for the modeling of charge transfer processes in hybrid organic&ndash ...
Corneliu I. Oprea, Mihai A. Gîrțu
doaj +1 more source
Synthesis and penicillin‐binding protein inhibitory assessment of dipeptidic 4‐phenyl‐β‐lactams from α‐amino acid‐derived imines [PDF]
Monocyclic beta-lactams revive the research field on antibiotics, which are threatened by the emergence of resistant bacteria. A six-step synthetic route was developed, providing easy access to new 3-amino-1-carboxymethyl-4-phenyl-beta-lactams, of which ...
Amoroso, Ana Maria+7 more
core +2 more sources
There is increasing concern about potential long-term effects of antibiotics on children’s health. Epidemiological studies have revealed that early-life antibiotic exposure can increase the risk of developing immune and metabolic diseases, and rodent ...
semanticscholar +1 more source
Penicillin Allergy Skin Testing in the Inpatient Setting
The consequences of a documented penicillin allergy in the medical record are especially troublesome in acutely ill, hospitalized patients. A penicillin allergy label may lead to alternative or second line therapies resulting in adverse drug events ...
Julie Ann Justo+3 more
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Introduction: Being labelled as allergic to different drugs results in patients receiving other treatments, which are more toxic, less effective and more expensive.
Miriam Sobrino-García+29 more
doaj +1 more source