Results 131 to 140 of about 205,895 (382)
Failure of Penicillin to Prevent Post-operative Chest Infection [PDF]
, 1957 Ellis Griffiths
openalex +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Some Factors Influencing the Production of Certain Biosynthetic Penicillins [PDF]
, 1957 H. G. Macmorine
openalex +2 more sources
The Estimation of Penicillins and Penicillin Destruction [PDF]
Journal of Pharmacy and Pharmacology, 1963 J. M. T. Hamilton-Miller +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan +4 more
wiley +1 more source
Group A Streptococcal Pharyngeal Infections: Diagnosis and Rational Antibacterial Therapy
Антибиотики и Химиотерапия, 2020 The problem of acute tonsillitis caused by Group A Beta-Hemolytic Streptococcus (GABHS) still remains relevant. This article provides data showing the revival of highly virulent GABHS infection and an increase in the incidence of complications (acute ...
B. S. Belov
doaj
THE BINDING OF PENICILLIN IN RELATION TO ITS CYTOTOXIC ACTION [PDF]
, 1954 Harry Eagle
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Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source