Results 201 to 210 of about 62,692 (265)

The Gut Microbiome and Diet Interact to Dictate Personalized Response to Broccoli Sprout Consumption

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
The study investigated how diet, the gut microbiome, and their interactions influence the production of different types of sulforaphane metabolites, specifically bioactive (have health benefits) and inert (do not have health benefits). Mediation analysis explored these tripartite relationships.
Alexandra Alexiev   +6 more
wiley   +1 more source

Single‐Nucleus Multiomic Analysis Reveals Immune–Metabolic Reprogramming Consistent With Maladaptive Trained Immunity in HIV‐Associated Neurocognitive Disorders

open access: yesGlia, Volume 74, Issue 8, August 2026.
Single‐nucleus multiomic profiling of postmortem brain reveals coordinated immune, metabolic, and epigenomic reprogramming in glia of people with HIV consistent with maladaptive trained immunity sustaining neuroinflammation in HAND. ABSTRACT HIV‐associated neurocognitive disorders (HAND) remain prevalent in people with HIV (PWH) despite effective ...
Siera Martinez   +8 more
wiley   +1 more source

Plasma and Brain Metabolomics Uncover Modulation of Bile Acid and Pentose Phosphate Pathways by <i>Melissa officinalis</i> in Obese Rat Model. [PDF]

open access: yesInt J Mol Sci
Aberkane FZ   +8 more
europepmc   +1 more source

Contrasting Effects of HT‐2 Toxin Exposure and ZIP6 Knockdown on Chondrocyte Extracellular Matrix Metabolism

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
HT‐2 toxin triggers chondrocyte damage and matrix metabolism disorders in KBD via suppressing ZIP6. ZIP6 knockdown alleviates these dysfunctions through FoxO, cAMP and TNF pathways, clarifying the molecular mechanism of cartilage injury. ABSTRACT Kashin‐Beck disease (KBD) is a chronic, endemic osteoarticular disorder associated with T‐2 toxin exposure,
Yang Liu   +10 more
wiley   +1 more source

Higher order synthetic lethals are keys to minimize cancer treatment effects on non-tumor cells. [PDF]

open access: yesPLoS One
Dehghan Manshadi M   +4 more
europepmc   +1 more source

In‐Vitro Evaluation of HIV/SARS‐CoV‐2 Co‐Infection Mediated Proteomic Changes in Astrocytes and Pericytes Reveals Altered Signaling Pathways Associated With Neurodegenerative Disorders

open access: yesJournal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Coronavirus disease 2019 (COVID‐19) survivors frequently experience a wide range of symptoms known as post‐acute sequelae of SARS‐CoV‐2 (PASC) or long COVID. Importantly, complications arising from microvascular dysfunction, blood‐brain barrier (BBB) disruption, and chronic neuroinflammation have been implicated in driving PASC within the ...
Arpan Acharya   +7 more
wiley   +1 more source

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