Results 121 to 130 of about 51,168 (257)

Plastic Diets Drive Microbiome and Metabolic Reprogramming in Wax Moth Larvae (Achroia grisella)

Archives of Insect Biochemistry and Physiology, Volume 122, Issue 3, July 2026.
Wax moth larvae (Achroia grisella) can consume LDPE and PLA, triggering polymer‐specific restructuring of the gut microbiome and host metabolism. LDPE feeding enriches Bacillus spp. and is associated with shifts in carbohydrate and amino‐acid pathways consistent with hydrocarbon processing, whereas PLA feeding enriches Enterococcus spp.
Rohan Shah, Anna Marcora, Angela Ruffell, Georgia M. Sinclair, Inka Vanwonterghem, Andrew Bissett, Andrew Hulthen, Gene Wijffels, Cate Paull, David J. Beale   +9 more
wiley   +1 more source

Metabolic Reprogramming by Andrographolide: Enhanced Pentose Phosphate Pathway and Antioxidant Capacity in Cortical Astrocytes. [PDF]

Pharmaceuticals (Basel)
Cisternas P, Ormazabal P, Gherardelli C, Bastías-Pérez M, Brito-Valenzuela J, Inestrosa NC.   +5 more
europepmc   +1 more source

Serum Proteomic Signatures of Rheumatoid Arthritis Risk and Response: Analysis of a Rheumatoid Arthritis Interception Trial

Arthritis &Rheumatology, Volume 78, Issue 7, Page 1403-1413, July 2026.
Objective Our study objective was to identify serum protein signatures associated with progression to rheumatoid arthritis (RA) and response to abatacept in at‐risk individuals. Methods A total of 440 serum samples from 118 APIPPRA (Arthritis Prevention In the Preclinical Phase of RA with Abatacept) study participants were selected from baseline to RA ...
Marianna Jasenecova, Carl Coyle, Alina Mihalovits, Sarah Ryan, Elizabeth Pook, Esperanza Perucha, Gabrielle Harker, Melody Chin, Sam Norton, Andrew P. Cope   +9 more
wiley   +1 more source

The MAFG-AS1/G6PD axis reduces platinum sensitivity in colorectal cancer through pentose phosphate pathway activation. [PDF]

J Transl Med
Kou JH, Yao Y, Li WJ, Zou J, Kong L, Zheng J, Yue YM, Han MM, Guo ST.   +8 more
europepmc   +1 more source

Multi‐Scale Hybrid Modeling to Predict Cell Culture Process With Metabolic Phase Transitions

Biotechnology and Bioengineering, Volume 123, Issue 7, Page 1745-1770, July 2026.
ABSTRACT To advance understanding of cellular metabolism and reduce batch‐to‐batch variability in cell culture processes, this study introduces a multi‐scale hybrid modeling framework designed to simulate and predict the dynamic behavior of CHO cell cultures undergoing metabolic phase transitions.
Keqi Wang, Sarah W. Harcum, Wei Xie
wiley   +1 more source

Oxidative pentose phosphate pathway is required for T cell activation and antitumor immunity. [PDF]

Proc Natl Acad Sci U S A
Chen Z, Olszewski KL, Ryseck RP, Xu X, Boyer JA, Peace CG, Shen Y, Bartman CR, Lynch L, Rabinowitz JD.   +9 more
europepmc   +1 more source

Vagus Nerve Stimulation Paired With Tones Alters the Auditory Cortex Proteome in a Rat Model of Rett Syndrome

Developmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Rett syndrome is a neurodevelopmental disorder caused by an X‐linked mutation of the MeCP2 gene. Individuals with Rett syndrome, as well as rodent models of this disorder, demonstrate abnormal cortical responses to sound, which impair auditory discrimination ability.
Isabella K. Myers, Fang Bian, Maria P. Solano, Yara El Zoghby, Diana Tavares‐Ferreira, Tanya Danaphongse, Crystal T. Engineer   +6 more
wiley   +1 more source

Pentose phosphate pathway fuels cGAS-STING signalling to boost function of intratumoral conventional dendritic cells. [PDF]

Nat Commun
Liu B, Geng Z, Huang Y, Yuan Y, Xu T, Zhu Y, Zhang J, Luo Z, Zhang S, Ding R, Tang R, Li Y, Hu Z.   +12 more
europepmc   +1 more source

Advances in the Study of Endometrial Receptivity and Glucose Metabolism Mechanisms in Insulin Resistance

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
This article systematically reviews how insulin resistance (IR) disrupts endometrial receptivity by interfering with glucose metabolism mechanisms, ultimately leading to infertility in patients with Polycystic Ovary Syndrome (PCOS). ABSTRACT Introduction Insulin resistance (IR) is one of the important pathologic bases of polycystic ovary syndrome (PCOS)
Si‐yan Huang, Shao‐rong Chen, Wei‐hong Chen, Ling‐tao Zheng, Jing Xu, Yan‐Chuan Shi, Shu Lin, Qi‐rong Shi   +7 more
wiley   +1 more source

IL21-STAT3 controls the pentose phosphate pathway to support metabolic reprogramming and tumor progression in chronic lymphocytic leukemia. [PDF]

Hemasphere
Del Prete R, Tusha V, Simon-Molas H, Gazziero VA, Nardi F, Drago R, Bartolini G, Licastro D, Malchiodi M, Mariottini C, Marotta G, Caravagna G, Bruscoli S, Eldering E, Gozzetti A, Bocchia M, Kabanova A.   +16 more
europepmc   +1 more source