ABSTRACT Grape marc (GM) is a polyphenol‐rich winery byproduct that remains underutilized due to its complex fiber matrix, which limits the bioaccessibility of bound phenolics. While lactic acid fermentation (LAF) can enhance the release of these compounds, the strain‐specific metabolic fate of GM phenolics during digestion and colonic fermentation ...
Ziyao Liu +4 more
wiley +1 more source
Neuronal loss of the pentose phosphate pathway in the living nervous system is causally linked to [NADPH] reduction and elevated oxidative stress. [PDF]
Müller S +6 more
europepmc +1 more source
CircNOLC1/KRT16 promotes colorectal cancer invasion and migration via c-met nuclear translocation and reprogramming of the oxidative pentose phosphate pathway. [PDF]
Wu H +10 more
europepmc +1 more source
Integrated GWAS and transcriptomics in a Canadian waterhemp biotype reveal mesotrione resistance is polygenic and metabolically driven. Significant SNPs and 187 herbicide‐responsive genes point to enhanced redox homeostasis, glutathione‐linked detoxification, lipid/secondary metabolism, and oxidative stress responses. Resistance arises from coordinated,
Martin Laforest +6 more
wiley +1 more source
White spot syndrome virus IE1 protein hijacks the host pentose phosphate pathway to fuel viral replication. [PDF]
Zhang J +5 more
europepmc +1 more source
Characterising the Pentose Phosphate Pathway
The Pentose Phosphate pathway(PPP) is a process that generates NADPH and pentoses. There are two phases in the pathway. The first is the oxidative phase (generation of NADPH) and the second is the non-oxidative synthesis of 5-carbon sugars.We present Stochastic,Deterministic, Metabolic Control Analysis and other Structural Analysis of this ...
openaire +1 more source
Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida +7 more
wiley +1 more source
Activation of the pentose phosphate pathway by microcurrent stimulation mediates antioxidant effects in inflammation-stimulated macrophages. [PDF]
Uemura M +11 more
europepmc +1 more source
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan +15 more
wiley +1 more source
Atovaquone-induced oxidative stress activates the pentose phosphate pathway and Immunogenic cell death in ovarian cancer. [PDF]
Betancourt Ponce M +5 more
europepmc +1 more source

