Results 141 to 150 of about 51,168 (257)

Comparative proteomics analysis of root and nodule mitochondria of soybean

Plant, Cell &Environment, Volume 49, Issue 7, Page 3482-3499, July 2026.
Abstract Legumes perform symbiotic nitrogen fixation through rhizobial bacteroids housed in specialised root nodules. The biochemical process is energy‐intensive and consumes a huge carbon source to generate sufficient reducing power. To maintain the symbiosis, malate is supplied by legume nodules to bacteroids as their major carbon and energy source ...
Wai‐Ching Sin, Jinhong Liu, Jia Yi Zhong, Hon‐Ming Lam, Boon Leong Lim   +4 more
wiley   +1 more source

NFATc1-mediated activation of the pentose phosphate pathway and cell cycle dysregulation collectively drive tumor progression. [PDF]

Oncogenesis
Zhang S, Xu G, Cao T, Yu F, Okotel M, Wu M, Wu S, Kasim V, Huang C.   +8 more
europepmc   +1 more source

Contextualized Metabolic Modelling Revealed Factors Affecting Isoflavone Accumulation in Soybean Seeds

Plant, Cell &Environment, Volume 49, Issue 7, Page 3543-3559, July 2026.
ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador, Ailin Liu, Ming‐Sin Ng, Yee‐Shan Ku, Siu H. J. Chan, Hon‐Ming Lam   +5 more
wiley   +1 more source

Targeting the pentose phosphate pathway mitigates graft-versus-host disease by rewiring alloreactive T cell metabolism. [PDF]

JCI Insight
Daneshmandi S, Ko E, Yan Q, Choi JE, Singh PK, Higashi RM, Lane AN, Fan TW, Qiu J, Hani S, Hippen KL, Wang J, McCarthy PL, Blazar BR, Mohammadpour H.   +14 more
europepmc   +1 more source

Poem: The pentose phosphate pathway [PDF]

Biochemistry and Molecular Biology Education, 2012
openaire   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Pentose Phosphate Pathway

, 2008
openaire   +3 more sources

Post-irradiation dietary restriction impairs hematopoiesis via inhibition of the pentose phosphate pathway in hematopoietic stem and progenitor cells. [PDF]

Cell Death Dis
Tao S, Su M, Yu C, Qiu X, Zou B, Qiu R, Wu Y, Liu L, Tao Z, Zhang L, Wang H, Tang D.   +11 more
europepmc   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, Volume 13, Issue 36, 29 June 2026.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

Correction: N6-methyladenosine modification of circ_0003215 suppresses the pentose phosphate pathway and malignancy of colorectal cancer through the miR-663b/DLG4/G6PD axis. [PDF]

Cell Death Dis
Chen B, Hong Y, Gui R, Zheng H, Tian S, Zhai X, Xie X, Chen Q, Qian Q, Ren X, Fan L, Jiang C.   +11 more
europepmc   +1 more source