Results 161 to 170 of about 51,168 (257)

Porcine reproductive and respiratory syndrome virus activates the pentose phosphate pathway via the ROS/HIF-1α/G6PD axis to promote viral replication. [PDF]

Virulence
Ma YX, Yang JM, Mei HT, Zeng L, Yang GY, Wang J, Ming SL, Chu BB.   +7 more
europepmc   +1 more source

Energy metabolism in osteoprogenitors and osteoblasts: Role of the pentose phosphate pathway. [PDF]

J Biol Chem
Catheline SE, Smith CO, McArthur M, Yu C, Brookes PS, Eliseev RA.   +5 more
europepmc   +1 more source

All You Can Eat Yeast: Substituting Hexose Transporters With AtSWEET7 Alleviates Glucose Repression, Enabling Simultaneous Utilization of Sugars in Renewable Feedstocks

Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1518-1530, June 2026.
ABSTRACT Yeast sugar transporters have highly evolved for preferential glucose transport, a significant roadblock for utilizing non‐glucose sugars in renewable feedstocks such as lignocellulosic biomass. To enable simultaneous transport of multiple sugars, native hexose transporters were replaced by SWEET7p from Arabidopsis thaliana in engineered ...
Nurzhan Kuanyshev, Degaulle Dai, Jungyeon Kim, Nam Kyu Kang, Ming‐Hsun Cheng, Vijay Singh, Yong‐Su Jin   +6 more
wiley   +1 more source

Carbohydrates and the oxidative branch of the pentose phosphate pathway modify <i>Bacteroides thetaiotaomicron</i> phage resistance by phase-variable S-layers. [PDF]

J Bacteriol
Fuentes JJ, Singh S, Pudlo NA, Heaver SL, Ley RE, Martens EC.   +5 more
europepmc   +1 more source

Metabolic Fingerprinting of Urine Reveals Metabolite Changes in Women With Breast Cancer

Cancer Medicine, Volume 15, Issue 6, June 2026.
This study uses metabolomics to compare urine, plasma and serum metabolite profiles across breast cancer, benign breast disease, symptomatic and healthy controls. Significant metabolic differences—especially in amino acids—were found between BC and other groups, with moderate correlations across biofluids, suggesting potential for non‐invasive BC ...
Nur Aimi Aliah Zainurin, Anuradha U. K. H. Bambarandhage, Michelle Moreno Escalona, Dimitra Ivanova, Tim Gate, Helen Tench, Manfred Beckman, Helen Phillips, Mandana Pennick, Luis A. J. Mur   +9 more
wiley   +1 more source

Neuronal glycogen breakdown mitigates tauopathy via pentose-phosphate-pathway-mediated oxidative stress reduction. [PDF]

Nat Metab
Bar S, Wilson KA, Hilsabeck TAU, Alderfer S, Dammer EB, Burton JB, Shah S, Holtz A, Carrera EM, Beck JN, Chen JH, Kauwe G, Seifar F, Shantaraman A, Tracy TE, Seyfried NT, Schilling B, Ellerby LM, Kapahi P.   +18 more
europepmc   +1 more source

LRP1 Activation Promotes Metabolic Reprogramming and Mrc1 Expression to Attenuate LPS‐Induced Cognitive Deficits: An Integrated Omics Analysis

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
LPS triggers neuroinflammation within the central nervous system. Conversely, the activation of LRP1 by SP16 mitigates insulin resistance, improves glucose metabolism, and facilitates the polarization of microglia toward an anti‐inflammatory M2‐like phenotype, which collectively contribute to the restoration of cognitive function.
Mengyao Qu, Yanan He, Lu Yu, Huikai Yang, Yixun Lu, Yingfu Li, Rui Wang, Miao Sun, Yulong Ma, Weidong Mi   +9 more
wiley   +1 more source

Genetic and Physiological Characterization of the Pentose Phosphate Pathway in the Yeast <i>Kluyveromyces lactis</i>. [PDF]

Int J Mol Sci
Bertels LK, Walter S, Heinisch JJ.
europepmc   +1 more source

Upregulated PKM2 Protects Dopaminergic Neurons From Oxidative Damage Through Nrf2 Transactivation in an MPTP‐Induced Mouse Model of Parkinson's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Oxidative stress induced by MPTP promotes hnRNP A1/A2–dependent alternative splicing toward PKM2 in dopaminergic neurons. Elevated PKM2 transactivates Nrf2, enhances antioxidant gene expression, and protects neurons from oxidative damage and degeneration.
Meng Mei, Qian‐qian Miao, Meng‐ke Li, Hao‐ran Wang, Jian‐hua Ding, Gang Hu, Yao Wei   +6 more
wiley   +1 more source

The brown fat-enriched exosomal miR-206-3p attenuates hepatic lipogenesis by decreasing pentose phosphate pathway. [PDF]

Life Metab
Yang LJ, Tang QK, Wang L, Song YJ, Xu ZY, Ma XN, Liu Y, Qian SW, Tang QQ, Tang Y.   +9 more
europepmc   +1 more source