Results 251 to 260 of about 200,892 (306)

On the biosynthesis of peptide ergot alkaloids

Experientia, 1974
Futterung vonl-Valyl-(1-14C)-l-valyl-l-prolin anClaviceps purpurea und Abbau des erhaltenen Ergocornins und Ergokryptins zeigt, dass dieses Tripeptid, ebenso wie andere fruher untersuchte Peptide, sehr wahrscheinlich kein freies Zwischenprodukt in der Biogenese der Mutterkornalkaloide vom Peptidtyp ist.
H G, Floss, M, Tcheng-Lin, H, Kobel, P, Stadler   +3 more
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Nonribosomal biosynthesis of peptide antibiotics

European Journal of Biochemistry, 1990
Peptide antibiotics are known to contain non‐protein amino acids, D‐amino acids, hydroxy acids, and other unusual constituents. In addition they may be modified by N‐methylation and cyclization reactions. Their biosynthetic origin has been connected in many cases to an enzymatic system referred to as the ‘thiotemplate multienzymic mechanism’.
H, Kleinkauf, H, von Döhren
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Biosynthesis and distribution of opioid peptides

Journal of Endocrinological Investigation, 1983
Group III opioid peptides are derived from proenkephalin B. The processing of this precursor peptide is still only partly understood and we still do not know how many final products come from proenkephalin B and whether Leu-enkephalin is produced from Group III peptides.
H, Imura, Y, Nakai, K, Nakao, S, Oki, I, Tanaka, H, Jingami, T, Yoshimasa, T, Tsukada, Y, Ikeda, M, Suda, M, Sakamoto   +10 more
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Biosynthesis of Small Peptides

Annual Review of Biochemistry, 1974
INTRODucTION 445 CURRENT PROBLEMS OF BIOSYNTHESIS OF SPECIFIC OLIGOPEPT1DES 446 Grarnicidin S and Tyrocidines 446 Linear Grarnicidins 450 Polymyxins 450 Bacitracins 451 Malforrain 452 Edeine 452 Aciinomyeins ’ 453 Quinoxaline Antibiotics .....
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Engineering the biosynthesis of fungal nonribosomal peptides

Natural Product Reports, 2023
Fungal nonribosomal peptides (NRPs) and the related polyketide–nonribosomal peptide hybrid products (PK–NRPs) are a prolific source of bioactive compounds, some of which have been developed into essential drugs.
Zhang, Liwen, Wang, Chen, Chen, Kang, Zhong, Weimao, Xu, Yuquan, Molnár, István   +6 more
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The Biosynthesis of Regulatory Peptides

American Review of Respiratory Disease, 1987
Abstract Regulatory peptides are synthesized in their cells of origin as large, usually inactive, precursors. The gene sequences encoding many peptides are now known. Although these indicate the primary structure of the precursor, it remains necessary to define the actual peptide products of cells expressing a particular gene.
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Biosynthesis of peptide–nucleobase hybrids in ribosomal peptides

Nature Chemical Biology
The main biopolymers in nature are oligonucleotides and polypeptides. However, naturally occurring peptide-nucleobase hybrids are rare. Here we report the characterization of the founding member of a class of peptide-nucleobase hybrid natural products with a pyrimidone motif from a widely distributed ribosomally synthesized and post-translationally ...
Zeng-Fei Pei, Natalia M. Vior, Lingyang Zhu, Andrew W. Truman, Satish K. Nair   +4 more
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Biosynthesis of Hypothalamic Peptides

1977
In this paper, I will attempt to summarize current knowledge about the biosynthesis of hypothalamic peptides of biological interest and will emphasize methodological aspects of peptide biosynthetic studies, a subject which I feel is of utmost importance at the present time.
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In Situ Biosynthesis of Peptide Arrays

2009
Polypeptide and protein arrays enable high-throughput screening capabilities for studying molecular interactions and profiling of biomarkers, and provide a powerful functional screening tool for peptidomics. To overcome the limitations of conventional arraying methods, we have exploited cell-free systems for generating arrays of polypeptides by direct ...
Mingyue, He, Oda, Stoevesandt
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Biosynthesis of Opioid Peptides

1990
The endogenous opioid peptides all contain the enkephalin sequence Tyr-Gly-Gly-Phe-Met and Tyr-Gly-Gly-Phe-Leu at their aminoterminus. Three distinct families of these peptides (endorphins, enkephalins and dynorphins) are present in different neuronal pathways within the central nervous system. Molecular genetics have shown that these three families of
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