Results 21 to 30 of about 319,110 (303)
Frontiers in Catalysis, 2023 In nonribosomal peptide synthesis, condensation (C) domains are key catalytic domains that most commonly link carrier protein bound substrates to form peptides or depsipeptides.
Y. T. Candace Ho +28 more
doaj +1 more source
Molecules, 2021 Fengycin, as a lipopeptide produced by Bacillus subtilis, displays potent activity against filamentous fungi, including Aspergillus flavus and Soft-rot fungus, which exhibits a wide range of potential applications in food industries, agriculture, and ...
Hedong Lu +11 more
doaj +1 more source
Diversity and biosynthetic potential of culturable microbes associated with toxic marine animals [PDF]
, 2013 Tetrodotoxin (TTX) is a neurotoxin that has been reported from taxonomically diverse organisms across 14 different phyla. The biogenic origin of tetrodotoxin is still disputed, however, TTX biosynthesis by host-associated bacteria has been reported.
Chau, Rocky +3 more
core +4 more sources
The benzodiazepine-like natural product tilivalline is produced by the entomopathogenic bacterium Xenorhabdus eapokensis. [PDF]
PLoS ONE, 2018 The pyrrolobenzodiazepine tilivalline (1) was originally identified in the human gut pathobiont Klebsiella oxytoca, the causative agent of antibiotic-associated hemorrhagic colitis.
Hendrik Wolff, Helge B Bode
doaj +1 more source
Frontiers in Microbiology, 2022 Circular bacteriocins, also known as bacterial head-to-tail cyclized peptides, are a subgroup of ribosomally synthesized and post-translationally modified peptides (RiPPs).
Fangfang Liu +3 more
doaj +1 more source
NG peptides: A novel family of neurophysin-associated neuropeptides [PDF]
, 2010 NOTICE: this is the author’s version of a work that was accepted for publication in GENE. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be ...
Bromham +20 more
core +1 more source
Put a Bow on It: Knotted Antibiotics Take Center Stage
Antibiotics, 2019 Ribosomally-synthesized and post-translationally modified peptides (RiPPs) are a large class of natural products produced across all domains of life. The lasso peptides, a subclass of RiPPs with a lasso-like structure, are structurally and functionally ...
Stephanie Tan +2 more
doaj +1 more source
Linking Peptide and Polyketide Biosynthesis.
The Journal of Antibiotics, 1995 organic chemist, natural chemistry within living organisms operates with protein catalysts. These catalysts assemble the reactants and perform their tasks in general in neutral aqueous media at ambient temperatures. To perform the synthesis of a complex metabolite, the proteins mayhave to interact in various ways.
H, Kleinkauf, H, von Döhren
openaire +3 more sources
Pass-back chain extension expands multimodular assembly line biosynthesis. [PDF]
, 2020 Modular nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) enzymatic assembly lines are large and dynamic protein machines that generally effect a linear sequence of catalytic cycles.
Huan, Tao +5 more
core
The role of the phosphopantetheinyltransferase enzyme, PswP, in the biosynthesis of antimicrobial secondary metabolites by Serratia marcescens Db10 [PDF]
, 2014 Phosphopantetheinyltransferase (PPTase) enzymes fulfil essential roles in primary and secondary metabolism in prokaryotes, archaea and eukaryotes. PPTase enzymes catalyse the essential modification of the carrier protein domain of fatty acid synthases ...
Amy J. Gerc +9 more
core +4 more sources