Results 31 to 40 of about 2,035,646 (256)
Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform. [PDF]
Drug DelivDelivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy.
Nyesiga B +6 more
europepmc +2 more sources
The Effects of Counter-Ions on Peptide Structure, Activity, and Applications
BiomoleculesPeptide drug development has emerged as a prominent area in pharmaceutical research due to its high specificity and therapeutic potential. However, their biological activity, stability, and bioavailability are significantly influenced by interactions ...
Ying Liu +9 more
doaj +1 more source
Peptide-based DNA delivery system
Medicine in Novel Technology and Devices, 2021 Gene therapy is defined as the ability to change individual's genetics by correcting genetic mutations or making site-specific alterations that target therapeutic treatment. The focus of gene therapy is optimization of delivery vectors. Peptide-based DNA
Pranjal Somvanshi, Shefali Khisty
doaj +1 more source
CIn recent years, carbon nanotubes have emerged as a potentially revolutionary material with numerous uses in biomedical applications. Compared to other nanoparticles, discrete multiwalled carbon nanotubes (dMWCNTs) have been shown to exhibit advantageous
Kevin Castillo +3 more
doaj +1 more source
International Journal of Nanomedicine, 2022 Taekwang Keum,1,2,* Gyubin Noh,1,2,* Jo-Eun Seo,1 Santosh Bashyal,1,2 Dong Hwan Sohn,1 Sangkil Lee1,2 1College of Pharmacy, Keimyung University, Daegu, Republic of Korea; 2Center for Forensic Pharmaceutical Science, Daegu, Republic of Korea&ast ...
Keum T +5 more
doaj
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Tumor Microenvironment–Responsive Peptide-Based Supramolecular Drug Delivery System
Frontiers in Chemistry, 2020 Physical and biochemical differences between tumor tissues and normal tissues provide promising triggering factors that can be utilized to engineer stimuli-responsive drug delivery platforms for cancer treatment.
Wenbo Zhang +3 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Peptide-conjugated micelles as a targeting nanocarrier for gene delivery
, 2017 The aim of this study was to develop peptide-conjugated micelles possessing epidermal growth factor receptor (EGFR) targeting ability for gene delivery.
Lin, Wen Jen;Chien, Wei Hsuan, 林文貞
core +1 more source