Results 31 to 40 of about 636,071 (310)
Membranes, 2022 A multitude of membrane active peptides exists that divides into subclasses, such as cell penetrating peptides (CPPs) capable to enter eukaryotic cells or antimicrobial peptides (AMPs) able to interact with prokaryotic cell envelops.
Niels Röckendorf +2 more
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Antibiotics, 2023 Antimicrobial peptides (AMPs) that exert multiple functions are considered promising candidates to combat the bacterial drug resistance crisis. Nowadays, targeted peptide modification has been widely recognised to improve biological activity and make up ...
Aifang Yao +9 more
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Exploration of the Determinants of Protein Structure and Stability by Protein Design [PDF]
, 2005 Optimization of Rotamers by Iterative Techniques (ORBIT) has been used to calculate novel sequences for several small proteins. A partial sequence design (20 of 28 residues) is described for the zinc finger Zif268 (beta-beta-alpha) motif.
Sarisky, Catherine Ann
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Design and synthesis of peptide-polymer conjugates and the characterization of their aggregation
, 2023 Kiick, Kristi L.Peptide-polymer conjugates are a hybrid class of materials that take advantage of natural and synthetic building blocks whose individual properties can be synergistically combined.
Paik, Bradford A.
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Design and optimization of peptide nanoparticles [PDF]
Journal of Nanobiotechnology, 2015 Various supra-molecular structures form by self-assembly of proteins in a symmetric fashion. Examples of such structures are viruses, some bacterial micro-compartments and eukaryotic vaults. Peptide/protein-based nanoparticles are emerging in synthetic biology for a variety of biomedical applications, mainly as drug targeting and delivery systems or as
Doll, Tais A. P. F. +2 more
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Biosensors, 2022 We have successfully designed a uranyl ion (U(VI)-specific peptide and used it in the fabrication of an electrochemical sensor. The 12-amino acid peptide sequence, (n) DKDGDGYIpTAAE (c), originates from calmodulin, a Ca(II)-binding protein, and contains ...
Channing C. Thompson, Rebecca Y. Lai
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Pharmaceuticals, 2023 Peptides, or short chains of amino-acid residues, are becoming increasingly important as active ingredients of drugs and as crucial probes and/or tools in medical, biotechnological, and pharmaceutical research.
Marko Jukič +3 more
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, 2009 Mastitis, or inflammation of the mammary gland, is the most common and expensive illness of dairy cows throughout the world. Although stress and physical injuries may give rise to inflammation of the udders, infections by bacteria or other microorganisms
Islas-Rodriguez, A.E. +20 more
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Disrupting Cu trafficking as a potential therapy for cancer
Frontiers in Molecular Biosciences, 2022 Copper ions play a crucial role in various cellular biological processes. However, these copper ions can also lead to toxicity when their concentration is not controlled by a sophisticated copper-trafficking system. Copper dys-homeostasis has been linked
Zena Qasem +11 more
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Synthetic Antimicrobial Peptide Design
Molecular Plant-Microbe Interactions, 1995 To guide the design of potential plant pathogen-resistance genes, synthetic variants of naturally occurring antimicrobial gene products were evaluated. Five 20-amino acid (ESF1, ESF4, ESF5, ESF6, ESF13), one 18-amino acid (ESF12), and one 17-amino acid (ESF17) amphipathic peptide sequences were designed, synthesized, and tested with in vitro bioassays.
W A, Powell, C M, Catranis, C A, Maynard
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