Results 41 to 50 of about 10,359,574 (255)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Peptide-cotton textiles with manifold antibacterial properties
, 2022 The development of antimicrobial materials recently have gained increased interest, especially for the development of medical devices as a practical way to prevent bacterial infections.
Marco Scocchi +3 more
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Requests from Companies and Requirements for Design Education in Brazil: where do they meet? [PDF]
, 2018 In this paper, we study what companies request from applicants for graphic design positions in Brazil. Based on a document analysis of 371 job advertisements, we uncover 35 different types of requests which we structure in terms of (1) Design ...
Person, Oscar +10 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2022 Schneider, Joel P.Self-assembly of de novo designed peptides is a promising approach towards fabrication of functional materials. Hydrogels are one such class of materials, which are highly hydrated and mechanically rigid, and show potential as scaffolds
Rughani, Ronak
core +1 more source
Design and Binding Affinity of Antisense Peptides for Snake Venom Neutralization
MoleculesSnakebites are a significant public health problem in many tropical and subtropical regions, causing extensive morbidity and mortality. Traditional snake antivenoms face multiple challenges, including allergenicity, high production costs, and logistical ...
Ivan Biruš +4 more
doaj +1 more source
Deep Learning for Novel Antimicrobial Peptide Design
Biomolecules, 2021 Antimicrobial resistance is an increasing issue in healthcare as the overuse of antibacterial agents rises during the COVID-19 pandemic. The need for new antibiotics is high, while the arsenal of available agents is decreasing, especially for the ...
Christina Wang, Sam Garlick, Mire Zloh
doaj +1 more source
PepINVENT: generative peptide design beyond natural amino acids. [PDF]
Chem SciPeptides play a crucial role in drug design and discovery whether as a therapeutic modality or a delivery agent. Non-natural amino acids (NNAAs) have been used to enhance the peptide properties such as binding affinity, plasma stability and permeability.
Geylan G +9 more
europepmc +2 more sources