Results 141 to 150 of about 473,894 (355)

Cognate peptide-receptor ligand mapping by directed phage display

Proteome Science, 2005
Background A rapid phage display method for the elucidation of cognate peptide specific ligand for receptors is described. The approach may be readily integrated into the interface of genomic and proteomic studies to identify biologically relevant ...
Stratmann Thomas, Kang Angray S
doaj   +1 more source

Signal Sequence-Dependent Orientation of Signal Peptide Fragments to Exosomes. [PDF]

Int J Mol Sci, 2022
Ono K, Niwa M, Suzuki H, Kobayashi NB, Yoshida T, Sawada M.   +5 more
europepmc   +1 more source

Faster graphical model identification of tandem mass spectra using peptide word lattices [PDF]

arXiv, 2014
Liquid chromatography coupled with tandem mass spectrometry, also known as shotgun proteomics, is a widely-used high-throughput technology for identifying proteins in complex biological samples. Analysis of the tens of thousands of fragmentation spectra produced by a typical shotgun proteomics experiment begins by assigning to each observed spectrum ...
arxiv  

3D In Vitro Glioma‐Neuron‐Astrocyte Biomimetic Composites Recapitulate Key Molecular Mechanisms Linked to Glioblastoma Multiforme Pathophysiology

Advanced Functional Materials, EarlyView.
Glioblastoma multiforme is the most devastating and incurable brain tumor. To better study this disease, a 3D model is developed using a hyaluronic acid‐based hydrogel combined with a multicellular approach. This model recapitulates in vivo brain stiffness, cell‐extracellular matrix and cell‐cell interactions and the tumor's hijacking function with the
Mateo S. Andrade Mier, Esra Türker, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Panthipa Suwannakot, Benedikt Gantert, Abhinav Singh, Vanessa Moessler, Annemarie Sodmann, Nicoletta Murenu, Joachim Schenk, Natascha Schaefer, Torsten Blunk, Aldo R. Boccaccini, Tessa C. Lühmann, Jörg Tessmar, Jeremy M. Crook, Eva Tomaskovic‐Crook, Paul D. Dalton, Gregor Lang, Robert Blum, Reiner Strick, Silvia Budday, Katrin G. Heinze, Carmen Villmann   +26 more
wiley   +1 more source

The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. [PDF]

, 1988
Autoantibodies to mitochondrial antigens are characteristic of the autoimmune liver disease primary biliary cirrhosis (PBC), but the precise antigenic determinants recognized by these antibodies have not been defined.
Ansari, A, Coppel, R, Gershwin, M, Leung, P, Van De Water, Judith   +4 more
core  

Differential behaviour of LPH‐(61–91)‐peptide in different model systems: Comparison of the opioid activities of LPH‐(61–91)‐peptide and its fragments [PDF]

, 1977
András Z. Rónai, László Gráf, József I. Székely, Zsuzsa Dunai-Kovàcs, S. Bajusz   +4 more
openalex   +1 more source

Sustained Release of Proteins Using Region‐Specific Tunable Degradability in Hydrogels through 3D Photopatterning and Complimentary Labile Bond Chemistry

Advanced Functional Materials, EarlyView.
A series of ultraviolet‐ and near‐infrared radiation sensitive photoactivatable hydrogels are developed that can be controlled spatiotemporally down to µm precisions using one‐ and two‐photon uncaging. The latent hydroxylamine‐, hydrazine‐, and amine uncaged moieties are used to photopattern a series of diverse proteins displaying complimentary ...
Tove Kivijärvi, Carmine P. Cerrato, Taha Behroozi Kohlan, Paul O’Callaghan, Johan Kreuger, Marie Arsenian‐Henriksson, Anna Finne‐Wistrand   +6 more
wiley   +1 more source

Comparative studies for amyloid beta degradation: "Neprilysin vs insulysin", "monomeric vs aggregate", and "whole Aβ₄₀ vs its peptide fragments". [PDF]

Biochem Biophys Rep, 2022
Kato D, Takahashi Y, Iwata H, Hatakawa Y, Lee SH, Oe T.   +5 more
europepmc   +1 more source

Transformer-based de novo peptide sequencing for data-independent acquisition mass spectrometry [PDF]

arXiv
Tandem mass spectrometry (MS/MS) stands as the predominant high-throughput technique for comprehensively analyzing protein content within biological samples. This methodology is a cornerstone driving the advancement of proteomics. In recent years, substantial strides have been made in Data-Independent Acquisition (DIA) strategies, facilitating ...
arxiv  

Cyanogen bromide cleavage of bovine fibrinogen. Identification of a dimeric N‐terminal peptide and two other disulfide containing fragments [PDF]

, 1973
Rupert Timpl, Rotraut Gollwitzer
openalex   +1 more source