Accurate Demarcation of Protein Domain Linkers based on Structural Analysis of Linker Probable Region [PDF]
International Journal of Computational Biology, 0001:01-19, 2012, 2012 In multi-domain proteins, the domains are connected by a flexible unstructured region called as protein domain linker. The accurate demarcation of these linkers holds a key to understanding of their biochemical and evolutionary attributes. This knowledge helps in designing a suitable linker for engineering stable multi-domain chimeric proteins. Here we
arxiv
Study of Hydrogenolytic Cleavage of Peptide-Resin Benzyl Ester Bonds for Synthesis of Protected Fragments of the Human Leukocyte Interferon [PDF]
, 1983 Anders Ljungqvist, Karl Folkers
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Advanced Healthcare Materials, EarlyView.This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto +2 more
wiley +1 more source
Conversion of proglucagon in pancreatic alpha cells: the major endproducts are glucagon and a single peptide, the major proglucagon fragment, that contains two glucagon-like sequences. [PDF]
, 1984 Christoph Patzelt, Emil Schiltz
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Advanced Healthcare Materials, EarlyView.This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey +5 more
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eLifeAn enzyme that remodels the cell wall of Enterococcus faecium helps these gut bacteria to divide and generate peptide fragments that enhance the immune response against cancer.
Rishika Prasad, Robert R Jenq
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Geometric Adjustment of T Cell‐Sensitive Nanorobots for Enhanced Stability
Advanced Healthcare Materials, EarlyView.For the long‐term use of live dendritic cell (DC)‐based vaccines, nano bone marrow dendritic cell (BMDC) originated T cell activators (nano‐BOTs) are synthesized. The geometric properties of nanoparticles are precisely modulated, enhancing their stability and T cell activation capacity.
Yoojin Lee +11 more
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Anthrax Vaccination, Gulf War Illness, and Human Leukocyte Antigen (HLA)
VaccinesWe report on a highly significant, positive association between anthrax vaccination and occurrence of Gulf War Illness (GWI) in 111 Gulf War veterans (42 with GWI and 69 controls).
Lisa M. James +5 more
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Is the Use of Surface-Enhanced Infrared Spectroscopy Justified in the Selection of Peptide Fragments That Play a Role in Substrate-Receptor Interactions? Adsorption of Amino Acids and Neurotransmitters on Colloidal Ag and Au Nanoparticles. [PDF]
J Phys Chem B, 2021 Proniewicz E +3 more
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Advanced Healthcare Materials, EarlyView.Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
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