Results 231 to 240 of about 2,313,645 (331)

High‐Concentration Antibody Formulation via Solvent‐Based Dehydration

Advanced Materials, EarlyView.
Amorphous solid antibodies are encapsulated into hydrogel microparticles through a solvent‐based dehydration process. The solvent extracts water from antibody solution droplets, causing the antibody to concentrate, and precipitation of the antibody into amorphous solid is induced.
Talia Zheng, Lucas Attia, Janet Teng, Patrick S. Doyle   +3 more
wiley   +1 more source

Separation of peptide fragments of a protein kinase C substrate fused to a β-hairpin by capillary electrophoresis. [PDF]

Anal Bioanal Chem, 2015
Zigoneanu IG, Sims CE, Allbritton NL.
europepmc   +1 more source

Autonomous Hydrogel Actuators Programmed by Endogenous Biochemical Logic for Dual‐Stage Morphing and Drug Release

Advanced Materials, EarlyView.
A 3D‐printed BSA–PEGDA bilayer actuator performs biochemical logic, bending autonomously in acid and releasing its drug payload only when both acid and pepsin are present. This dual‐stage, enzyme‐gated mechanism enables autonomous catch‐and‐release motion and controlled gastric drug delivery, representing a programmable soft material powered by ...
Yuchen Liu, Harischandra Potthuri, Alejandro Sosnik, Luai R. Khoury   +3 more
wiley   +1 more source

CLINICAL SIGNIFICANCE OF N-TERMINAL FRAGMENT OF NATRIURETIC PEPTIDE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS WHO DO NOT RECEIVE PATHOGENETIC THERAPY

, 2017
T. A. Panafidina, M. A. Sokhova, Т. В. Попкова, Д. С. Новикова, Е Н Александрова, Yu. O. Korsakova, А. В. Волков   +6 more
openalex   +1 more source

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source

Effect of position-specific single-point mutations and biophysical characterization of amyloidogenic peptide fragments identified from lattice corneal dystrophy patients. [PDF]

Biochem J, 2017
Anandalakshmi V, Murugan E, Leng EGT, Ting LW, Chaurasia SS, Yamazaki T, Nagashima T, George BL, Peh GSL, Pervushin K, Lakshminarayanan R, Mehta JS.   +11 more
europepmc   +1 more source

Reconstitution of Escherichia coli thioredoxin from complementing peptide fragments obtained by cleavage at methionine-37 or arginine-73.

, 1975
Ivan Slabý, Arne Holmgren
openalex   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

A crystalline synthetic peptide representing the epitope of a monoclonal antibody raised against synthetic interferon-a1 fragment 111 - 166

, 1985
Michel Aguet, Prathima Salgam, Bernd Gutte, Heinz Arnheiter   +3 more
openalex   +2 more sources

Treatment with Plasma Activated (Salt) Water Sterilizes Macromolecular Coatings While Maintaining Their Integrity and Functionality

Advanced Materials Interfaces, EarlyView.
PDMS samples were covalently coated with mucin glycoproteins and then treated with either plasma activated water (PAW) or saline (PAS) as a means of disinfection. The samples could be successfully sterilized without compromising the structural integrity or functionality of those coatings.
Bernardo Miller Naranjo, Markus Ahrens, Ádám Nemes, Petra Mela, Oliver Lieleg   +4 more
wiley   +1 more source