Results 241 to 250 of about 473,894 (355)

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

Advanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang, Qiang Tian, Zhenli Lei, Shuxin Wang, Nan Cheng, Zhen Wang, Xianqin Jiang, Xuqun Zheng, Wenjing Xu, Minyan Ye, Longwei Zhao, Meiyun Wen, Jianlou Niu, Weijian Sun, Pingping Shen, Zhifeng Huang, Xiaokun Li   +16 more
wiley   +1 more source

Amyloid-like Behavior of Site-Specifically Citrullinated Myelin Oligodendrocyte Protein (MOG) Peptide Fragments inside EBV-Infected B-Cells Influences Their Cytotoxicity and Autoimmunogenicity. [PDF]

Biochemistry, 2019
Araman C, van Gent ME, Meeuwenoord NJ, Heijmans N, Marqvorsen MHS, Doelman W, Faber BW, 't Hart BA, Van Kasteren SI.   +8 more
europepmc   +1 more source

Inhibition of prolyl endopeptidase by synthetic peptide fragments of human .BETA.-casein.

, 1991
Minao ASANO, Noriki Nio, Yasuo Ariyoshi
openalex   +2 more sources

Synthesis and Interfacial Studies of Peptide Fragments Related to the PA-22-2 Region of Laminin [PDF]

, 2000
D. Polo, M. A. Alsina, Isabel Haro, F. Reig   +3 more
openalex   +1 more source

A peptide fragment of pepsin containing methionine [PDF]

Chemistry of Natural Compounds, 1969
V. M. Stepanov, Yu. S. Kuznetsov, V. I. Vasenev   +2 more
openaire   +2 more sources

Inhibition of Aberrant Activated Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism

Advanced Science, EarlyView.
LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su, Xuemei Fan, Yaoyao Zou, Guangtao Fu, Shiqi Feng, Xiaoxue Wang, Yongmei Yu, Lin Li, Zhenhua Bian, Rongrong Huang, Linmang Qin, Jiping Chen, Qin Zeng, Kai Yan, Caiyue Gao, Zhexiong Lian, Xin Li, Yang Li   +17 more
wiley   +1 more source

Analysis of isotopic labeling in peptide fragments by tandem mass spectrometry. [PDF]

PLoS One, 2014
Allen DK, Evans BS, Libourel IG.
europepmc   +1 more source

Amino Acids and Peptides. XXXIV. Synthesis of Mouse Metallothionein I.(1). Synthesis of Dotriacontapeptide Corresponding to C-Terminal Sequence 30-61 (.ALPHA.-Fragment) of Mouse Metallothionein I and Related Peptides and Examination of Their Heavy Metal-Binding Properties.

, 1992
Satoshi Matsumoto, Shigeru NAKAYAMA, Yasuhiro NISHIYAMA, Yoshio Okada, Kyong-Son MIN, Satomi ONOSAKA, Kéiichi Tanaka   +6 more
openalex   +2 more sources

A Kinetic Model of Vertebrate 20S Proteasome Accounting for the Generation of Major Proteolytic Fragments from Oligomeric Peptide Substrates [PDF]

, 2000
Hermann‐Georg Holzhütter, Peter‐Michael Kloetzel   +1 more
openalex   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source