Results 261 to 270 of about 473,894 (355)

What are the minimal folding seeds in proteins? Experimental and theoretical assessment of secondary structure propensities of small peptide fragments. [PDF]

open access: yesChem Sci
Osifová Z   +9 more
europepmc   +1 more source

Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang   +16 more
wiley   +1 more source

The GhWL1‐GhH1‐GhGA2OX1 Transcriptional Module Regulates Cotton Leaf Morphology

open access: yesAdvanced Science, EarlyView.
This study identified GhWL1 as a key gene involved in regulating leaf development through analysis of a T‐DNA insertion mutant. The GhWL1‐GhH1 complex is shown to positively regulate GhGA2OX1 by directly binding to its promoter, thereby establishing the GhWL1‐GhH1‐GhGA2OX1 module as a critical pathway in leaf development.
Jingjing Zhan   +12 more
wiley   +1 more source

Functional Signal Peptides Bind a Soluble N-terminal Fragment of SecA and Inhibit Its ATPase Activity [PDF]

open access: hybrid, 2001
Terry L. Triplett   +5 more
openalex   +1 more source

Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

open access: yesAdvanced Science, EarlyView.
VPS72 overexpression activates mTORC1 signaling, subsequently promoting lipid synthesis and driving HCC progression. VPS72 modulates the epigenetic landscape of ATF3 promoter, such as H2A.Z acetylation reduction and DNA methylation increase, which results in ATF3 repression and subsequent activation of mTORC1.
Qinglin Zhang   +4 more
wiley   +1 more source

Osteoclast Inhibitory Peptide 2 Inhibits Osteoclast Formation via Its C-Terminal Fragment [PDF]

open access: bronze, 2001
Sun Jin Choi   +3 more
openalex   +1 more source

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