Multicomponent Peptide Hydrogels as an Innovative Platform for Cell-Based Tissue Engineering in the Dental Pulp [PDF]
Pharmaceutics, 2021 In light of the increasing levels of antibiotic resistance, nanomaterials and novel biologics are urgently required to manage bacterial infections. To date, commercially available self-assembling peptide hydrogels have not been studied extensively for ...
Marina E. Afami +5 more
doaj +2 more sources
Self-Assembled Peptide Hydrogels in Regenerative Medicine [PDF]
Gels, 2023 Regenerative medicine is a complex discipline that is becoming a hot research topic. Skin, bone, and nerve regeneration dominate current treatments in regenerative medicine.
Shuangyang Li +5 more
doaj +2 more sources
RNA extraction from self-assembling peptide hydrogels to allow qPCR analysis of encapsulated cells. [PDF]
PLoS ONE, 2018 Self-assembling peptide hydrogels offer a novel 3-dimensional platform for many applications in cell culture and tissue engineering but are not compatible with current methods of RNA isolation; owing to interactions between RNA and the biomaterial.
Kyle A Burgess +5 more
doaj +4 more sources
Incorporation of Natural and Recombinant Collagen Proteins within Fmoc-Based Self-Assembling Peptide Hydrogels [PDF]
Gels, 2022 Hydrogel biomaterials mimic the natural extracellular matrix through their nanofibrous ultrastructure and composition and provide an appropriate environment for cell–matrix and cell–cell interactions within their polymeric network.
Mattia Vitale +5 more
doaj +2 more sources
Morphological Characterizations and Mineralized Repair of Natural Tooth Cracks Via Self-Assembling Peptide Hydrogels [PDF]
International Dental JournalIntroduction and aims: This study aimed to investigate the distribution and morphology of cracks in natural cracked teeth and evaluate the potential of self-assembling peptide hydrogels (L-gel: Nap-FFG-DHTKE and D-gel: Nap-DFDFG-DHTKE) as biomimetic ...
Zhenying Zheng +8 more
doaj +2 more sources
Regulated anthocyanin release through novel pH-responsive peptide hydrogels in simulated digestive environment [PDF]
Food Chemistry: XThe instability of anthocyanins significantly reduces their bioavailability as food nutrients. This proof-of-concept study aimed to develop efficient carriers for anthocyanins to overcome this challenge.
Wenjun Li +7 more
doaj +2 more sources
Preclinical Efficacy of Pro- and Anti-Angiogenic Peptide Hydrogels to Treat Age-Related Macular Degeneration [PDF]
Bioengineering, 2021 Pro-angiogenic and anti-angiogenic peptide hydrogels were evaluated against the standard of care wet age-related macular degeneration (AMD) therapy, Aflibercept (Eylea®).
Amanda Acevedo-Jake +7 more
doaj +2 more sources
Mesenchymal stem cells aligned and stretched in self-assembling peptide hydrogels [PDF]
HeliyonThe presented research highlights a novel approach using fmoc-protected peptide hydrogels for the encapsulation and stretching of mesenchymal stem cells (MSCs).
Farzaneh Fouladgar +8 more
doaj +2 more sources
Functionalized peptide hydrogels: enabling dynamic stage-adaptive modulation for wound healing [PDF]
Frontiers in Cell and Developmental BiologyFunctionalized peptide hydrogels represent an emerging class of intelligent wound dressings that dynamically coordinate the multifaceted process of wound healing through stage-specific bioactivities.
Xi-Kun Ma +3 more
doaj +2 more sources
Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop [PDF]
Nature Communications, 2023 The amino acid sequences of peptides determine their self-assembling properties. Accurate prediction of peptidic hydrogel formation, however, remains a challenging task.
Tengyan Xu +9 more
doaj +2 more sources