Results 61 to 70 of about 53,655 (285)
Recent research of peptide-based hydrogel in nervous regeneration
Bioactive MaterialsNeurological disorders exert significantly affect the quality of life for patients, necessitating effective strategies for nerve regeneration. Both traditional autologous nerve transplantation and emerging therapeutic approaches encounter scientific ...
Chunmei Xie +7 more
doaj +1 more source
Molecular modeling to predict peptide accessibility for peptide-functionalized hydrogels [PDF]
Biointerphases, 2017 Peptide-functionalized (PF) hydrogels are being widely investigated by the tissue engineering and regenerative medicine communities for a broad range of applications because of their unique potential to mimic the natural extracellular matrix and promote tissue regeneration. In order for these complex material systems to perform their intended bioactive
Xianfeng, Li +3 more
openaire +2 more sources
Direct observation of peptide hydrogel self-assembly
Chemical Science, 2022 To facilitate the characterization of phase-transitioning molecules, site-specific non-perturbative infrared probes are leveraged for continuous observation of the self-assembly of fibrils in a peptide hydrogel following stopped-flow initiation.
Zoë C. Adams +8 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato +9 more
wiley +1 more source
Self assembled bi-functional peptide hydrogels with biomineralization-directing peptides [PDF]
Biomaterials, 2010 A peptide-based hydrogel has been designed that directs the formation of hydroxyapatite. MDG1, a twenty-seven residue peptide, undergoes triggered folding to form an unsymmetrical beta-hairpin that self-assembles in response to an increase in solution ionic strength to yield a mechanically rigid, self supporting hydrogel. The C-terminal portion of MDG1
Sarikaya, Mehmet +5 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
MoleculesThe bioavailability, release, and stability of pharmaceuticals under physicochemical conditions is the major cause of drug candidates failing during their clinical trials.
Adelaide R. Mashweu, Vladimir A. Azov
doaj +1 more source
Heterotypic Supramolecular Hydrogels Formed by Noncovalent Interactions in Inflammasomes
Molecules, 2020 The advance of structural biology has revealed numerous noncovalent interactions between peptide sequences in protein structures, but such information is less explored for developing peptide materials.
Adrianna N. Shy +3 more
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Peptide-Based Hydrogels: Template Materials for Tissue Engineering
Journal of Functional Biomaterials, 2023 Tissue and organ regeneration are challenging issues, yet they represent the frontier of current research in the biomedical field. Currently, a major problem is the lack of ideal scaffold materials’ definition.
Roya Binaymotlagh +2 more
doaj +1 more source
Polypeptide gels incorporating the exotic functional aromatic amino acid 4-amino-L-phenylalanine [PDF]
, 2018 High-molecular-weight polypeptides with functional aromatic side chains, poly(4-amino-l-phenylalanine), were prepared by the metal-initiated polymerization of the Nα-carboxyanhydride of the corresponding amino acid, which is a microbial derivative of ...
Ali, Mohammad Asif +4 more
core +1 more source