Results 111 to 120 of about 281,224 (300)

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

Advanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang, Rui Chen, Yu Chen, Haowen Lu, Yuchen Qian, Zhiheng Gao, Zheming Shen, Xiaofei Zheng, Huilin Yang, Jun Zou, Yusen Qiao   +10 more
wiley   +1 more source

Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues

Advanced Materials Interfaces, EarlyView.
ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike, Dhananjay V. Deshmukh, Mark W. Tibbitt, Céline Labouesse   +3 more
wiley   +1 more source

Towards an understanding of peptide-inorganic interactions

, 2013
This study has contributed to the developing understanding of fundamental principles through which interactions at peptide-inorganic interfaces occur. The inorganic materials; crystalline zinc oxide (ZnO) and platinum (Pt) together with specific binding ...
Limo, MJ
core  

Association of N-terminal pro-brain natriuretic peptide with cognitive function and depression in elderly people with type 2 diabetes [PDF]

, 2012
<p>Background: Type 2 diabetes mellitus is associated with risk of congestive heart failure (CHF), cognitive dysfunction and depression. CHF itself is linked both to poor cognition and depression.
Deary, Ian J., Rebecca M Reynolds, Ian J Deary, Price Jackie F., Welsh, Paul, Reynolds, Rebecca M., Mark W J Strachan, Sattar Naveed, Welsh Paul, Paul Welsh, Feinkohl, Insa, Price, Jackie F.; id_orcid, Reynolds Rebecca M., Strachan Mark W. J., Price, Jackie F., Strachan, Mark W.J., Sattar, Naveed, Deary, Ian, Edinburgh Type 2 Diabetes Study-ET2DS Investigators, Deary Ian J., ?, ?, Strachan, Mark W. J., Naveed Sattar, Jackie F Price, Feinkohl Insa, Insa Feinkohl   +25 more
core   +1 more source

Minimally Invasive Delivery of Optical Nanosensors Using Injectable Hydrogels

Advanced Materials Interfaces, EarlyView.
Injectable peptide hydrogels offer a minimally invasive delivery platform for single‐walled carbon nanotube (SWCNT)‐based near‐infrared fluorescent sensors, enabling real‐time measurement of drug concentrations. Encapsulated SWCNTs show a dose‐dependent fluorescence response across physiologically relevant concentrations and retain their fluorescence ...
Shirel Kleiner, Gili Bisker
wiley   +1 more source

High content analysis to determine cytotoxicity of the antimicrobial peptide, melittin and selected structural analogs

, 2011
Antimicrobial peptides (AMPs) are naturally occurring entities with potential as pharmaceutical candidates and/or food additives. They are present in many organisms including bacteria, insects, fish and mammals.
O\u27Brien, Peter J., David J. Brayden, Baird, Alan W., Peter J. O’Brien, Marc Devocelle, Devocelle, Marc, Sam Maher, Alan W. Baird, Maher, Sam, Edwin G. Walsh, Walsh, Edwin G., O'Brien, Peter J., Brayden, David James   +12 more
core   +1 more source

Light Switchable Ionic Conductivity of Arylazopyrazole Modified Polysiloxanes

Advanced Materials Technologies, EarlyView.
We present a polysiloxane functionalized with a novel arylazopyrazole dye that undergoes reversible photoisomerization. Upon lithium bis(trifluoromethanesulfonyl)imide addition and UV irradiation, the polymer exhibits a shift in tan(d) toward higher frequencies and enhanced ionic conductivity.
Malte S. Beccard, Thulasinath Raman Venkatesan, Michael Bauer, Valentin Razvan Lupu, Philipp Scheidegger, Francesco Taddei, Frank A. Nüesch, Dorina M. Opris   +7 more
wiley   +1 more source

Isolation of a Colon Tumor Specific Binding Peptide Using Phage Display Selection

Neoplasia: An International Journal for Oncology Research, 2003
Colorectal cancer is the third most common malignancy in the United States. Improved detection sensitivity of early colorectal neoplasms would have important clinical applications.
Kimberly A. Kelly, David A. Jones
doaj   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Peptide ligands that bind to staphylococcal enterotoxin B (SEB)

, 2004
Staphylococcal enterotoxin B (SEB) is a primary toxin that causes food poisoning. It also acts as a superantigen that interacts with the major histocompatibility complex class II molecule (MHCII) and T cell receptor (TCR) to activate large amounts of T ...
Wang, Guangquan
core