Results 11 to 20 of about 257,591 (258)
Frontiers in Microbiology, 2022 BackgroundChagas is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. On the order of seven million people are infected worldwide and current therapies are limited, highlighting the urgent need for new interventions.
Jéssica I. de Paula +5 more
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Bioactive Peptides from Libraries [PDF]
Chemistry & Biology, 2005 New ligands for a variety of biological targets can be selected from biological or synthetic combinatorial peptide libraries. The use of different libraries to select novel peptides with potential therapeutic applications is reviewed. The possible combination of molecular diversity provided by combinatorial libraries and a rational approach derived ...
Falciani, Chiara +3 more
openaire +5 more sources
Large‐scale survey and database of high affinity ligands for peptide recognition modules
Molecular Systems Biology, 2020 Many proteins involved in signal transduction contain peptide recognition modules (PRMs) that recognize short linear motifs (SLiMs) within their interaction partners.
Joan Teyra +13 more
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Acrylamide neurotoxicity on the cerebrum of weaning rats
Neural Regeneration Research, 2015 The mechanism underlying acrylamide-induced neurotoxicity remains controversial. Previous studies have focused on acrylamide-induced toxicity in adult rodents, but neurotoxicity in weaning rats has not been investigated.
Su-min Tian +5 more
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Molecules, 2014 We have achieved site-specific conjugation of several haloacetamide derivatives into designated cysteines on bacteriophage T7-displayed peptides, which are fused to T7 capsid protein gp10.
Yuuki Tokunaga +5 more
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Neural Regeneration Research, 2015 Ferumoxytol, an iron replacement product, is a new type of superparamagnetic iron oxide approved by the US Food and Drug Administration. Herein, we assessed the feasibility of tracking transplanted human adipose-derived stem cells labeled with ...
Yan Yin +5 more
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Screening technology of cyclic peptide library based on gene encoding
Medicine in Drug Discovery, 2022 As a powerful tool for the discovery of peptide compounds, high-throughput library screening technology can also perform multitarget screening with high chemical diversity as a condition, which accelerates the process of exploring high-affinity peptide ...
Yangqiang Chen +5 more
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Investigation of Nose-to-Brain Transportation of Peptide-Displaying Bacteriophage Particles Using Phage Display Method [PDF]
Pharmaceutical SciencesBackground: Brain drug delivery is of paramount significance in CNS-related diseases as blood brain barrier (BBB) permeability is not feasible for many pharmaceutical agents.
Hakimeh Kanaani +5 more
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Neural Regeneration Research, 2015 Cell therapy using stem cell transplantation against cerebral ischemia has been reported. However, it remains controversial regarding the optimal time for cell transplantation and the transplantation route.
Seyed Mojtaba Hosseini +4 more
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Peripheral nerve repair: a hot spot analysis on treatment methods from 2010 to 2014
Neural Regeneration Research, 2015 Therapeutic strategies for neurological deficits and for promoting nerve regeneration after peripheral nerve injuries have received much focus in clinical research.
Guang-yao Liu +3 more
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