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Phage-displayed peptide libraries [PDF]
Current Opinion in Biotechnology, 1998 Over the past year, significant advances have been achieved through the use of phage-displayed peptide libraries. A wide variety of bioactive molecules, including antibodies, receptors and enzymes, have selected high-affinity and/or highly-specific peptide ligands from a number of different types of peptide library.
M B, Zwick, J, Shen, J K, Scott
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Neural Regeneration Research, 2015 Hydrogen can relieve tissue-damaging oxidative stress, inflammation and apoptosis. Injection of hydrogen-rich saline is an effective method for transporting molecular hydrogen.
Jian-long Wang +6 more
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Neural Regeneration Research, 2015 With advances in biomedical methods, tissue-engineered materials have developed rapidly as an alternative to nerve autografts for the repair of peripheral nerve injuries. However, the materials selected for use in the repair of peripheral nerve injuries,
Yuan Gao +6 more
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Hydrogen sulfide intervention in focal cerebral ischemia/reperfusion injury in rats
Neural Regeneration Research, 2015 The present study aimed to explore the mechanism underlying the protective effects of hydrogen sulfide against neuronal damage caused by cerebral ischemia/reperfusion.
Xin-juan Li +6 more
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Frontiers in Medicine, 2020 Middle ear ailments include a broad range of pathological conditions. Otitis media is the leading middle ear disease of childhood, which incurs significant health care resources in developed countries and, in developing countries, causes significant ...
Arwa Kurabi +7 more
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Trinucleotide cassettes increase diversity of T7 phage-displayed peptide library
BMC Biotechnology, 2007 Background Amino acid sequence diversity is introduced into a phage-displayed peptide library by randomizing library oligonucleotide DNA. We recently evaluated the diversity of peptide libraries displayed on T7 lytic phage and M13 filamentous phage and ...
McMahon James B +4 more
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Methodologies for Backbone Macrocyclic Peptide Synthesis Compatible With Screening Technologies
Frontiers in Chemistry, 2020 Backbone macrocyclic structures are often found in diverse bioactive peptides and contribute to greater conformational rigidity, peptidase resistance, and potential membrane permeability compared to their linear counterparts.
Koki Shinbara +4 more
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Neural Regeneration Research, 2015 The Wnt/β-catenin signaling pathway plays a crucial role in neural development, axonal guidance, neuropathic pain remission and neuronal survival. In this study, we initially examined the effect of rapamycin on the Wnt/β-catenin signaling pathway after ...
Kai Gao +7 more
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Curcumin improves synaptic plasticity impairment induced by HIV-1gp120 V3 loop
Neural Regeneration Research, 2015 Curcumin has been shown to significantly improve spatial memory impairment induced by HIV-1 gp120 V3 in rats, but the electrophysiological mechanism remains unknown.
Ling-ling Shen +11 more
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Molecules, 2014 The design, synthesis and screening of diversity-oriented peptide libraries using a “libraries from libraries” strategy for the development of inhibitors of α1-antitrypsin deficiency are described. The major buttress of the biochemical approach presented
Yi-Pin Chang, Yen-Ho Chu
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