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Overlapping Peptide Library to Map Qa-1 Epitopes in a Protein. [PDF]
J Vis Exp, 2017 Xu Y +4 more
europepmc +1 more source
Evaluation of Endosomal Protonation on Peptide Binding to Class II Major Histocompatibility Complex Molecules [PDF]
, 2013 Crane, Kyle L.
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Combinatorial Chemistry & High Throughput Screening, 2008
Peptide aptamers are molecules that bind to protein targets and are able to interfere with their functions. In the past, important achievements have been made using such peptide aptamers in different approaches and for various purposes. Peptide aptamers are comprised of a variable peptide region of 8 to 20 amino acids in length, which is displayed by a
Corina, Borghouts +2 more
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Peptide aptamers are molecules that bind to protein targets and are able to interfere with their functions. In the past, important achievements have been made using such peptide aptamers in different approaches and for various purposes. Peptide aptamers are comprised of a variable peptide region of 8 to 20 amino acids in length, which is displayed by a
Corina, Borghouts +2 more
openaire +2 more sources
Current Opinion in Biotechnology, 1994
Over the past year, great strides have been made in the design of peptide libraries, and new approaches have been developed for identifying peptide ligands. The libraries comprise large collections of peptides, ranging from 1 million to 1 billion different sequences, which can be screened using monoclonal and polyclonal antibodies, receptors, enzymes ...
J K, Scott, L, Craig
openaire +2 more sources
Over the past year, great strides have been made in the design of peptide libraries, and new approaches have been developed for identifying peptide ligands. The libraries comprise large collections of peptides, ranging from 1 million to 1 billion different sequences, which can be screened using monoclonal and polyclonal antibodies, receptors, enzymes ...
J K, Scott, L, Craig
openaire +2 more sources
Peptide Vaccines and Peptide Libraries
Biological Chemistry, 2001Synthetic immunogens, containing built-in adjuvanticity, B cell, T helper cell and CTL epitopes or mimotopes, are ideal and invaluable tools to study the immune response with respect to antigen processing and presentation. This serves as a basis for the development of complete and minimal vaccines which do not need large carrier proteins, further ...
K H, Wiesmüller +2 more
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Phage Displayed Peptide Libraries
Combinatorial Chemistry & High Throughput Screening, 1999Peptide libraries may be constructed by grafting, in vitro, random DNA sequences into a carrier gene and then introducing the degenerate hybrid coding sequence into an expression organism. This review will focus on phage display, which was the first expression organism for peptide library expression to be described and which still maintains ...
Cesareni G, Castagnoli L, Cestra G
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Methods in enzymology, 1997
Combinatorial chemistry is a rapidly developing field. It is now considered as one of the most important recent advances in medicinal chemistry. In addition to drug lead identification, combinatorial chemistry can also be applied to the optimization of the initial lead.
M, Lebl, V, Krchnák
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Combinatorial chemistry is a rapidly developing field. It is now considered as one of the most important recent advances in medicinal chemistry. In addition to drug lead identification, combinatorial chemistry can also be applied to the optimization of the initial lead.
M, Lebl, V, Krchnák
openaire +3 more sources
Methods, 1996
Filamentous phage particles have been central in the construction of libraries displaying vast numbers of random peptides. These random peptides can be antigenically presented as fusions to coat proteins III and VIII of the phage. The isolation of ligate-reactive phage from an immense background of nonspecific phage is achieved by the biopanning ...
, Daniels, , Lane
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Filamentous phage particles have been central in the construction of libraries displaying vast numbers of random peptides. These random peptides can be antigenically presented as fusions to coat proteins III and VIII of the phage. The isolation of ligate-reactive phage from an immense background of nonspecific phage is achieved by the biopanning ...
, Daniels, , Lane
openaire +2 more sources