Results 271 to 280 of about 379,196 (358)

Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine

Advanced Science, EarlyView.
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li, Huiqin Chen, Qiaofeng Shen, Yingshuang Liu, Pingping Li, Yuqi Ma, Yugang Wang, Shengkai Li, Xueqing Yan, Liyu Liu, Jianwei Shuai, Min Wu, Qi Ouyang, Feng‐Ming (Spring) Kong, Gen Yang   +14 more
wiley   +1 more source

A Degenerate Peptide Library Approach to Reveal Sequence Determinants of Methyllysine-Driven Protein Interactions. [PDF]

Front Cell Dev Biol, 2020
Kupai A, Vaughan RM, Dickson BM, Rothbart SB.   +3 more
europepmc   +1 more source

Retrovirally Delivered Random Cyclic Peptide Libraries Yield Inhibitors of Interleukin-4 Signaling in Human B Cells [PDF]

, 2002
Todd M. Kinsella, Cara T. Ohashi, Amy Grace Harder, George Yam, Weiqun Li, Beau R. Peelle, Erlina S. Pali, Mark K. Bennett, Susan M. Molineaux, Deborah Anderson, Esteban S. Masuda, Donald G. Payan   +11 more
openalex   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

Evolving a Peptide: Library Platforms and Diversification Strategies. [PDF]

Int J Mol Sci, 2019
Bozovičar K, Bratkovič T.
europepmc   +1 more source

A De novo Peptide from a High Throughput Peptide Library Blocks Myosin A -MTIP Complex Formation in Plasmodium falciparum. [PDF]

Int J Mol Sci, 2020
Anam ZE, Joshi N, Gupta S, Yadav P, Chaurasiya A, Kahlon AK, Kaushik S, Munde M, Ranganathan A, Singh S.   +9 more
europepmc   +1 more source

Selection of v-Abl Tyrosine Kinase Substrate Sequences from Randomized Peptide and Cellular Proteomic Libraries Using mRNA Display [PDF]

, 2002
Thomas P. Cujec, Patrícia Flores de Medeiros, Phil Hammond, Cecil Rise, Brent Kreider   +4 more
openalex   +1 more source

Cancer Specific CAIX‐Targeting Supramolecular Lysosome‐Targeting Chimeras (Supra‐LYTAC) for Targeted Protein Degradation

Advanced Science, EarlyView.
Spatiotemporal Supra‐LYTAC formation near cancerous membrane via CAIX‐targeting is achieved. As a result of generation of Supra‐LYTAC, POI trafficking into lysosome is significantly implemented for targeted protein degradation. Abstract Recently, targeted protein degradation (TPD) strategies have emerged as a promising solution to tackle undruggable ...
Dohyun Kim, Gyeongseok Yang, Chaelyeong Lim, Gaeun Park, Jaemo Lee, Youjung Sim, Ja‐Hyoung Ryu   +6 more
wiley   +1 more source

Routine evaluation of HBV-specific T cell reactivity in chronic hepatitis B using a broad-spectrum T-cell epitope peptide library and ELISpot assay. [PDF]

J Transl Med
Wu Y, Liu X, Mao Y, Ji R, Xia L, Zhou Z, Ding Y, Li P, Zhao Y, Peng M, Qiu J, Shen C.   +11 more
europepmc   +1 more source

A Genetically Encoded, Phage-Displayed Cyclic-Peptide Library. [PDF]

Angew Chem Int Ed Engl, 2019
Wang XS, Chen PC, Hampton JT, Tharp JM, Reed CA, Das SK, Wang DS, Hayatshahi HS, Shen Y, Liu J, Liu WR.   +10 more
europepmc   +1 more source