Results 51 to 60 of about 254,967 (163)

Calibr improves spectral library search for spectrum-centric analysis of data independent acquisition proteomics

Scientific Reports, 2022
Identifying peptides and proteins from mass spectrometry (MS) data, spectral library searching has emerged as a complementary approach to the conventional database searching. However, for the spectrum-centric analysis of data-independent acquisition (DIA)
Jen-Hung Wang, Wai-Kok Choong, Ching-Tai Chen, Ting-Yi Sung   +3 more
doaj   +1 more source

Peptide substrate identification for yeast Hsp40 Ydj1 by screening the phage display library

Biological Procedures Online, 2004
We have identified a peptide substrate for molecular chaperone Hsp40 Ydj1 by utilizing the combination of phage display library screening and isothemol titration calirimetry (ITC).
Li Jingzhi, Sha Bingdong
doaj   +1 more source

Shotgun Phage Display - Selection for Bacterial Receptins or other Exported Proteins

Biological Procedures Online, 2003
Shotgun phage display cloning involves construction of libraries from randomly fragmented bacterial chromosomal DNA, cloned genes, or eukaryotic cDNAs, into a phagemid vector.
Jacobsson Karin, Rosander Anna, Bjerketorp Joakim, Frykberg Lars   +3 more
doaj   +1 more source

On the origin of non-specific binders isolated in the selection of phage display peptide libraries

Frontiers in Microbiology
Over the recent decades, phage display has been used successfully to identify a variety of peptides with diagnostic and therapeutic applications. Despite the significant role of this technology in the pharmaceutical industry, the affinity selection of ...
Babak Bakhshinejad, Babak Bakhshinejad, Andreas Kjaer, Andreas Kjaer   +3 more
doaj   +1 more source

Identification of a cardiac specific protein transduction domain by in vivo biopanning using a M13 phage peptide display library in mice.

PLoS ONE, 2010
BackgroundA peptide able to transduce cardiac tissue specifically, delivering cargoes to the heart, would be of significant therapeutic potential for delivery of small molecules, proteins and nucleic acids.
Maliha Zahid, Brett E Phillips, Sean M Albers, Nick Giannoukakis, Simon C Watkins, Paul D Robbins   +5 more
doaj   +1 more source

Isolation of a Colon Tumor Specific Binding Peptide Using Phage Display Selection

Neoplasia: An International Journal for Oncology Research, 2003
Colorectal cancer is the third most common malignancy in the United States. Improved detection sensitivity of early colorectal neoplasms would have important clinical applications.
Kimberly A. Kelly, David A. Jones
doaj   +1 more source

Fuel-Driven Dynamic Combinatorial Peptide Libraries

Angewandte Chemie International Edition
Dynamic combinatorial chemistry (DCC) creates libraries of molecules that are constantly interchanging in a dynamic combinatorial library. When a library member self-assembles, it can displace the equilibria, leading to emergent phenomena like its selection or even its replication.
Fabian Späth, Héctor Soria‐Carrera, Michele Stasi, Judit Sastre, Brigitte A. K. Kriebisch, Job Boekhoven   +5 more
openaire   +3 more sources

Molecular Characterization of a cDNA Encoding of an Anionic Cysteine-Free Antimicrobial Peptide From the Iranian Scorpion Odontobuthus Doriae Venom Glands

Pharmaceutical and Biomedical Research, 2022
Background: The venom peptides from the scorpion fauna of Iran have been poorly characterized so far. Objectives: In this study, we identified a cDNA encoding of an anionic cysteine-free antimicrobial peptide from the Iranian yellow scorpion odontobuthus
Amir Jalali, Masoud Mahdavinia, Hamid Galehdari, Masoumeh Baradaran, Davood Valdi-Biranvand, Maryam Naderi Soorki   +5 more
doaj  

Bicyclic Peptide Library Screening for the Identification of Gαi Protein Modulators. [PDF]

J Med Chem, 2023
Pepanian A, Binbay FA, Roy S, Nubbemeyer B, Koley A, Rhodes CA, Ammer H, Pei D, Ghosh P, Imhof D.   +9 more
europepmc   +1 more source

Targeting Protein-Protein Interfaces with Peptides: The Contribution of Chemical Combinatorial Peptide Library Approaches. [PDF]

Int J Mol Sci, 2023
Monti A, Vitagliano L, Caporale A, Ruvo M, Doti N.   +4 more
europepmc   +1 more source