Results 261 to 270 of about 483,403 (312)
Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting
Advanced Materials, EarlyView.CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu +4 more
wiley +1 more source
Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma
Advanced Materials, EarlyView.A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura +19 more
wiley +1 more source
Amyloid‐Templated Ceria Nanozyme Reinforced Microneedle for Diabetic Wound Treatments
Advanced Materials, EarlyView.This work demonstrates an effective strategy for synthesizing high‐catalytic and stable nanozymes, and introduces the first example of amyloid‐ceria nanozymes reinforced microneedle which features a complex, synergistic catalytic behavior combining superoxide dismutase and catalase‐like activities, promoting to remodel the infection microenvironment in
Qize Xuan +13 more
wiley +1 more source
Studies on heart. XXI. Amino acid sequence of antiarrhythmic peptide (AAP) isolated from atria.
, 1982 SHIGERU AONUMA +3 more
openalex +2 more sources
Advanced Materials, EarlyView.Upconversion nanoparticle‐covalent organic framework core–shell particles provide enhanced contrast for optoacoustic imaging by leveraging the optical absorption of upconversion luminescence within the covalent organic framework matrix. Beyond their role as contrast agents, these particles enable customizable therapeutic agent loading and release, as ...
Dong Wook Kim +8 more
wiley +1 more source
Advanced Materials, EarlyView.Biological nanopores are highly promising tools for single‐molecule biosensors, but the fragile supporting lipid membranes is a major bottleneck. An alternative hybrid membrane is presented, comprising phospholipids and block co‐polymers, that can be functionalized by a broad variety of nanopores for single‐molecule sensing.
Edo Vreeker +6 more
wiley +1 more source
The amino acid sequence of a salivary peptide (F-A) with histamine-releasing property.
, 1985 Katsumi Sugiyama +2 more
openalex +2 more sources
A Multifunctional Binder for Current‐Collector‐Free Zn Powder Anodes
Advanced Materials, EarlyView.By introducing abundant polar groups as Zn2+ absorption sites and hydrogen bond arrays, a protein structure‐derived binder for ZP anode and iodine cathode is proposed. This design can regulate the Zn2+ flux, benefit the formation of free‐standing electrode, inhibit the side reactions, suppress the shuttle effect of polyiodides, and enable the large ...
Yanbo Wang +10 more
wiley +1 more source