Results 21 to 30 of about 109,234 (306)
Comparison of Collisional Fragmentation Pathways of Sodiated and Protonated Cyclic Peptide Analogs [PDF]
Zhipu Xuebao, 2023 Cyclic peptides and their related species have been shown a unique class of molecules characterized by their biological function and structural diversity.
DU Meng-ying1;JIAO Lu-yang1;XU Yi-cheng1;LI Shu-qi1;CUI Yong-liang1;ZHANG Sen1;KONG Xiang-lei1,2,3
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More than skin deep: cyclic peptides as wound healing and cytoprotective compounds
Frontiers in Cell and Developmental Biology, 2023 The prevalence and cost of wounds pose a challenge to patients as well as the healthcare system. Wounds can involve multiple tissue types and, in some cases, become chronic and difficult to treat.
Ying-Chiang J. Lee +3 more
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Anion recognition by cyclic peptides [PDF]
Chemical Communications, 2015 Cyclic peptides provide excellent scaffolds for anion recognition and improved binding affinity and selectivity has been achieved through peptide backbone rigidification and the introduction of side chains bearing anion recognition groups.
Elmes, Robert B. P. +1 more
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Cyclic Peptides for the Treatment of Cancers: A Review
Molecules, 2022 Cyclic peptides have been widely reported to have therapeutic abilities in the treatment of cancer. This has been proven through in vitro and in vivo studies against breast, lung, liver, colon, and prostate cancers, among others.
Dalifa Ramadhani +3 more
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Nature Communications, 2021 Cyclic peptides are of particular interest due to their pharmacological properties, but their design for binding to a target protein is challenging. Here, the authors present a computational “anchor extension” methodology for de novo design of cyclic ...
Parisa Hosseinzadeh +17 more
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Frontiers in Molecular Biosciences, 2023 Genetically-encoded combinatorial peptide libraries are convenient tools to identify peptides to be used as therapeutics, antimicrobials and functional synthetic biology modules. Here, we report the identification and characterization of a cyclic peptide,
Stefano Rosa +11 more
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, 2022 Cyclic peptides are able to extend the druggable space of pharmaceutical targets, due to their size, conformational behavior, and high proportion of hydrogen bond donors and acceptors.
Sereina, Riniker +6 more
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CHIMIA, 2021 Proteins with large and flat binding sites as well as protein–protein interactions are considered ' undruggable ' with conventional small-molecule drugs.
Stephanie M. Linker +4 more
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Marine Cyclic Peptides: Antimicrobial Activity and Synthetic Strategies
Marine Drugs, 2022 Oceans are a rich source of structurally unique bioactive compounds from the perspective of potential therapeutic agents. Marine peptides are a particularly interesting group of secondary metabolites because of their chemistry and wide range of ...
Ricardo Ribeiro +3 more
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Structural Diversity and Biological Activities of Fungal Cyclic Peptides, Excluding Cyclodipeptides
Molecules, 2017 Cyclic peptides are cyclic compounds formed mainly by the amide bonds between either proteinogenic or non-proteinogenic amino acids. This review highlights the occurrence, structures and biological activities of fungal cyclic peptides (excluding ...
Xiaohan Wang +4 more
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