Results 31 to 40 of about 864,219 (301)
G3: Genes, Genomes, Genetics, 2022 In recent years, a variety of fungal cyclic peptides with interesting bioactivities have been discovered. For many of these peptides, the biosynthetic pathways are unknown and their elucidation often holds surprises.
Eva Vogt +3 more
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Química Nova, 2009 Natural peptides are outstanding as the most promising macromolecules in the search for new drugs, especially those of cyclic nature. The higher plants revealed a very peculiar composition of their cyclic peptides, which distinguish themselves by a "head-
Douglas Gatte Picchi +4 more
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Cyclic peptides- small and big and their conformational aspects [PDF]
, 1985 Cyclic peptides form an interesting class of compounds for study by conformational analysis, by virtue of their unique conformational features and biological properties.
Ramakrishnan, C. +2 more
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Directed Evolution of Bicyclic Peptides for Therapeutic Application
CHIMIA, 2013 Many naturally occurring cyclic peptides or derivatives thereof are used as therapeutics such as the human hormones vasopressin and oxytocin or the antibiotics vancomycin and daptomycin.
Philippe Diderich, Christian Heinis
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Isolating cyclic peptides from linear peptides
, 2023 Poster and abstract presented at the FYRE in STEM Showcase, 2023.Research project completed at the Department of Chemistry and Biochemistry.For decades, medicines treating ailments from autoimmune diseases to fungal infections have included peptides ...
Mandapaka, Hyma +2 more
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Natural Cyclic Peptides as an Attractive Modality for Therapeutics: A Mini Review
Molecules, 2018 Peptides are important biomolecules which facilitate the understanding of complex biological processes, which in turn could be serendipitous biological targets for future drugs. They are classified as a unique therapeutic niche and will play an important
Muna Ali Abdalla, Lyndy J. McGaw
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Ligation Technologies for the Synthesis of Cyclic Peptides
, 2019 Cyclic peptides have been attracting a lot of attention in recent decades, especially in the area of drug discovery, as more and more naturally occurring cyclic peptides with diverse biological activities have been discovered.
Hoi Yee Chow +7 more
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Docking Flexible Cyclic Peptides with AutoDock CrankPep [PDF]
, 2019 While a new therapeutic cyclic peptide is approved nearly every year, docking large macrocycles has remained challenging. Here, we present a new version of our peptide docking software AutoDock CrankPep (ADCP), extended to dock peptides cyclized through ...
Yuqi, Zhang +3 more
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
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Royal Society Open Science, 2021 Improving the sustainability of synthesis is a major goal in green chemistry, which has been greatly aided by the development of asymmetric transition metal catalysis.
Richard C. Brewster +3 more
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