Results 41 to 50 of about 2,785,119 (387)

Peptide Bioinformatics- Peptide Classification Using Peptide Machines [PDF]

open access: yes, 2008
Peptides scanned from whole protein sequences are the core information for many peptide bioinformatics research such as functional site prediction, protein structure identification, and protein function recognition. In these applications, we normally need to assign a peptide to one of the given categories using a computer model.
openaire   +2 more sources

Preferred Configurations of Peptide–Peptide Interactions

open access: yesThe Journal of Physical Chemistry A, 2013
The natural and fundamental proclivities of interaction between a pair of peptide units are examined using high-level ab initio calculations. The NH···O H-bonded structure is found to be the most stable configuration of the N-methylacetamide (NMA) model dimer, but only slightly more so than a stacked arrangement.
Adhikari, U., Scheiner, Steve
openaire   +5 more sources

Selection of experimental animals and modeling methods in developmental dysplasia of the hip research

open access: yesEFORT Open Reviews
Developmental dysplasia of the hip (DDH) is a common neonatal musculoskeletal condition characterized by hip instability and inadequate acetabular coverage. If untreated, it can lead to osteoarthritis, chronic pain, and eventual hip replacement.
Yu Rao   +6 more
doaj   +1 more source

Anti-Influenza A Viral Butenolide from Streptomyces sp. Smu03 Inhabiting the Intestine of Elephas maximus

open access: yesViruses, 2018
Actinobacteria are a phylum of bacteria known for their potential in producing structurally diversified natural products that are always associated with a broad range of biological activities.
Fangfang Li   +8 more
doaj   +1 more source

Blood Levels of Neuropeptide 26RFa in Relation to Anxiety and Aggressive Behavior in Humans—An Exploratory Study

open access: yesBrain Sciences, 2023
26RFa, also referred to as QRFP, is a hypothalamic neuropeptide mainly known for its role in the regulation of appetite and glucose metabolism. Its possible relevance to emotional regulation is largely unexplored.
Henning Værøy   +5 more
doaj   +1 more source

Dual-acting stapled peptides target both HIV-1 entry and assembly [PDF]

open access: yes, 2013
Background: Previously, we reported the conversion of the 12-mer linear and cell-impermeable peptide CAI to a cell-penetrating peptide NYAD-1 by using an i,i + 4 hydrocarbon stapling technique and confirmed its binding to the C-terminal domain (CTD ...
Bhargava, P.   +12 more
core   +2 more sources

Antibacterial Peptides [PDF]

open access: yesAntibiotics, 2020
As natural host defense compounds produced by numerous prokaryotic and eukaryotic life forms, antimicrobial peptides (AMPs) are now emerging as solid candidate chemotherapeutic drugs to fight against the various types of pathogenic Gram-positive and Gram-negative bacteria, especially those resistant to current antibiotics [...]
openaire   +4 more sources

Structural and thermodynamic approach to peptide immunogenicity [PDF]

open access: yes, 2008
In the conventional paradigm of humoral immunity, B cells recognize their cognate antigen target in its native form. However, it is well known that relatively unstable peptides bearing only partial structural resemblance to the native protein can trigger
Ascherman, DP, Camacho, CJ, Katsumata, Y
core   +3 more sources

A Condensation-Ordering Mechanism in Nanoparticle-Catalyzed Peptide Aggregation [PDF]

open access: yes, 2009
Nanoparticles introduced in living cells are capable of strongly promoting the aggregation of peptides and proteins. We use here molecular dynamics simulations to characterise in detail the process by which nanoparticle surfaces catalyse the self ...
A Aggeli   +62 more
core   +6 more sources

Microvascular Metrics on Diabetic Retinopathy Severity: Analysis of Diabetic Eye Images from Real-World Data

open access: yesBiomedicines
Objective: To quantify microvascular lesions in a large real-world data (RWD) set, based on single central retinal fundus images of diabetic eyes from different origins, with the aim of validating its use as a precision tool for classifying diabetic ...
Cristina Cuscó   +4 more
doaj   +1 more source

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