Results 81 to 90 of about 8,551 (180)

Temperature-dependent regulation of bacterial cell division hydrolases by the coordinated action of a regulatory RNA and the ClpXP protease

The Cell Surface
A defining feature of bacteria is the peptidoglycan cell wall which provides structural integrity and prevents osmotic lysis. While peptidoglycan hydrolases are required for daughter cell separation, dysregulated cell wall degradation may result in cell ...
Viktor H. Mebus, Larissa M. Busch, Morten Børre, Tobias K. Nielsen, Martin Saxtorph Bojer, Camilla Henriksen, Maria D. Barbuti, Danae M. Angeles, Kamilla Brejndal, Stephan Michalik, Manuela Gesell Salazar, Morten Kjos, Uwe Völker, Birgitte H. Kallipolitis, Dorte Frees   +14 more
doaj   +1 more source

The Plant Pathogen Xanthomonas campestris pv. campestris Exploits N-Acetylglucosamine during Infection

mBio, 2014
N-Acetylglucosamine (GlcNAc), the main component of chitin and a major constituent of bacterial peptidoglycan, is present only in trace amounts in plants, in contrast to the huge amount of various sugars that compose the polysaccharides of the plant cell
Alice Boulanger, Claudine Zischek, Martine Lautier, Stevie Jamet, Pauline Rival, Sébastien Carrère, Matthieu Arlat, Emmanuelle Lauber   +7 more
doaj   +1 more source

Transcriptome Sequencing Reveals Distinct Stress Response of Listeria monocytogenes 6179 During Logarithmic and Stationary Growth Phases

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Visualization of significantly enriched KEGG pathways under different stress conditions: (A) stationary phase cells exposed to 15 mM hydrogen peroxide, (B) stationary phase cells exposed to 1% lactic acid, (C) logarithmic phase cells exposed to 15 mM hydrogen peroxide, and (D) logarithmic phase cells exposed to 1% lactic acid.
Jessica L. Strathman‐Runyan, Bienvenido W. Tibbs‐Cortes, Stephan Schmitz‐Esser   +2 more
wiley   +1 more source

A Single Dual-Function Enzyme Controls the Production of Inflammatory NOD Agonist Peptidoglycan Fragments by Neisseria gonorrhoeae

mBio, 2017
Neisseria gonorrhoeae gonococcus (GC) is a Gram-negative betaproteobacterium and causative agent of the sexually transmitted infection gonorrhea. During growth, GC releases lipooligosaccharide (LOS) and peptidoglycan (PG) fragments, which contribute ...
Jonathan D. Lenz, Kathleen T. Hackett, Joseph P. Dillard   +2 more
doaj   +1 more source

Molecular Cloning and Functional Analysis of Holin and Endolysin From Escherichia Phage UE‐M6 as Potential Antibacterial Agents

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
We isolated phage UE‐M6 from wastewater and subsequently cloned, expressed, and purified its encoded endolysin (UE‐lysin) and holin (UE‐holin). Our results demonstrate that the combined application of UE‐lysin and UE‐holin exhibits significantly greater antibacterial activity than either protein alone, indicating a synergistic interaction between the ...
Hira Niaz, Mikael Skurnik, Fazal Adnan
wiley   +1 more source

A novel peptidoglycan deacetylase modulates daughter cell separation in E. coli.

PLoS Genetics
Peptidoglycan hydrolases facilitate bacterial cell wall growth by creating space for insertion of new material and allowing physical separation of daughter cells.
Víctor M Hernández-Rocamora, Alessandra M Martorana, Aitana Belloso, Daniel Ballesteros, Marta Zaccaria, Amilcar J Perez, Bogdan I Iorga, David Abia, Joe Gray, Eefjan Breukink, Jie Xiao, Manuel Pazos, Alessandra Polissi, Waldemar Vollmer   +13 more
doaj   +1 more source

The Pathogenic Neisseria Use a Streamlined Set of Peptidoglycan Degradation Proteins for Peptidoglycan Remodeling, Recycling, and Toxic Fragment Release

Frontiers in Microbiology, 2019
Neisseria gonorrhoeae and Neisseria meningitidis release peptidoglycan (PG) fragments from the cell as the bacteria grow. For N. gonorrhoeae these PG fragments are known to cause damage to human Fallopian tube tissue in organ culture that mimics the ...
Ryan E. Schaub, Joseph P. Dillard
doaj   +1 more source

Comprehensive analysis of peptidoglycan hydrolases in Caulobacter crescentus

, 2016
The peptidoglycan (PG) sacculus is a large macromolecule enclosing most bacterial cells. During progression of the cell cycle, it needs to be continuously remodelled to enable elongation of the cell body and, finally, cell division.
Zielinska, Aleksandra, Thanbichler, Martin (Prof. Dr.)   +1 more
openaire   +3 more sources

Bacillus subtilis CwlP of the SP-β Prophage Has Two Novel Peptidoglycan Hydrolase Domains, Muramidase and Cross-linkage Digesting dd-Endopeptidase [PDF]

, 2010
I Putu Sudiarta, Tatsuya Fukushima, Junichi Sekiguchi   +2 more
openalex   +1 more source

Systemic application of bone-targeting peptidoglycan hydrolases as a novel treatment approach for staphylococcal bone infection. [PDF]

mBio, 2023
Keller AP, Huemer M, Chang C-C, Mairpady Shambat S, Bjurnemark C, Oberortner N, Santschi MV, Zinsli LV, Röhrig C, Sobieraj AM, Shen Y, Eichenseher F, Zinkernagel AS, Loessner MJ, Schmelcher M.   +14 more
europepmc   +1 more source