Results 101 to 110 of about 12,487 (241)
Inspired by the process of water oxidation during photosynthesis, researchers have developed mononuclear and polynuclear transition metal complexes as homogeneous water oxidation catalysts.
Molly , McAuliffe +11 more
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Synthesis of a novel tricyclic peptidomimetic Scaffold
, 2008 An efficient method to synthesize a novel rigid tricyclic peptidomimetic scaffold through ring-closure of amino-functionalized bicyclic 2-pyridones has been discovered.
Sellstedt, Magnus,, Almqvist, Fredrik,
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ADAM17 and its proteolytic targets in disease pathogenesis
The FEBS Journal, EarlyView.ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
Synthesis of a Novel Tricyclic Peptidomimetic Scaffold
, 2016 An efficient method to synthesize a novel rigid tricyclic peptidomimetic scaffold through ring-closure of amino-functionalized bicyclic 2-pyridones has been discovered.
Magnus Sellstedt (1280439) +1 more
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GelsSupramolecular gels were developed by taking advantage of an assembly of small dipeptides containing pyrrolo-pyrazole scaffolds. The dipeptides were prepared through a robust and ecofriendly synthetic approach from the commercially available starting ...
Enrica Chiesa +6 more
doaj +1 more source
Chirality, Volume 38, Issue 7, July 2026.A practical and straightforward approach to optically active erythro 3‐amino‐2‐hydroxy acids and its application to the enantioselective synthesis of 3‐phenylisoserine and of the marine natural product 3‐amino‐2‐hydroxy‐6‐methylheptanoic acid is reported.
Marilena Caporale +4 more
wiley +1 more source
��-turn peptidomimetic cyclic compounds
, 2001 Proteolytically stable small molecule -turn peptidomimetic compounds have been identified as agonists or antagonists of neurotrophin receptors, such as TrkA. A compound of particular interest binds the immunoglobulin-like C2 region of the extracellular
Saragovi, Horacio Uri, Burgess, Kevin
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The Anti-Amoebic Activity of a Peptidomimetic against Acanthamoeba castellanii
, 2022 Acanthamoeba is a free-living protozoan known to cause keratitis most commonly, especially among contact lens wearers. Treatment of Acanthamoeba keratitis is challenging as Acanthamoeba can encyst from the active form, a trophozoite, into a hibernating ...
Peguda, HK ; https://orcid.org/ +5 more
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Pest Management Science, Volume 82, Issue 7, Page 6842-6863, July 2026.A two‐pronged screen of small molecules – (1) on recombinant kinin receptor and (2) through topical application – identifies kinin receptor antagonists, feeding behavior modulators, and new mosquitocidal molecules. Abstract BACKGROUND Aedes aegypti and Culex quinquefasciatus mosquitoes are primary vectors for numerous human and animal pathogens and ...
Bianca M. Henriques‐Santos +1 more
wiley +1 more source
, 2014 Yeliz Utku Konca,1 Kent Kirshenbaum,2 Ronald N Zuckermann3 1Department of Chemistry, Koc University, Istanbul, Turkey; 2Department of Chemistry, New York University, New York, NY, 3Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA ...
Kirshenbaum K +2 more
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