Results 121 to 130 of about 14,095 (224)

Editorial: Contemporary Perspective on 5-HT2C Receptor Function and Its Pharmacological Targeting

Frontiers in Pharmacology, 2020
Philippe De Deurwaerdère, Abdeslam Chagraoui, Abdeslam Chagraoui, Kathryn A. Cunningham   +3 more
doaj   +1 more source

DAPEG, a Modular Peptidomimetic Concept for Intracellular Delivery: Architecture, Trajectory, and Outlook in the Context of Peptidomimetic Transfection Reagents. [PDF]

ACS Omega
Mallek W, Mirecka G, Wysocka M.
europepmc   +1 more source

Deconstruction of Aspartic Protease Inhibitors Enables Fragment-Based Discovery of Plasmepsin V Inhibitors. [PDF]

ChemMedChem
Skvorcova M, Ruduša L, Zelencova-Gopejenko D, Jirgensons A, Bobrovs R.   +4 more
europepmc   +1 more source

Discovery of novel peptidomimetics against HSP90-HOP interactions towards improved cancer therapeutics using machine learning strategies. [PDF]

Front Bioinform
Perumal S, Karuppasamy R.
europepmc   +1 more source

A Small Molecule Substrate Mimic to Inhibit Bacterial Hsp70 Chaperone Function. [PDF]

Chembiochem
Upadhyay T, Kumari R, Gangarde YM, Potteth US, Roychowdhury R, Das A, Saxena D, Maitra R, Chopra S, Saraogi I.   +9 more
europepmc   +1 more source

Systematic Evaluation of Peptidomimetic Modifications in a Major Histocompatibility Complex Class I Model Epitope: A Framework for Immunogenic Antigen Design. [PDF]

ACS Chem Biol
Newkirk SE, Kelly JJ, Hourn N, Bhandari S, Spencer N, Pires MM.   +5 more
europepmc   +1 more source

Extracellularly Activatable Conjugates of RGD Peptidomimetics and Cryptophycin for α_Vβ₃-Targeted Cancer Therapy. [PDF]

Chemistry
Seißenschmidt D, Hartung H, Kammer J, Sewald N.   +3 more
europepmc   +1 more source

Guanidinium-rich cell-penetrating peptidomimetic-doxorubicin conjugates show linker-dependent, reduced acute toxicity to cardiomyocytes and normal breast epithelium while retaining activity against a HER2-positive breast cancer model (SKBR3 spheroids). [PDF]

Front Chem
Mallek W, Bublewicz H, Mirecka G, Godziątkowski K, Piwkowska A, Lesner A, Wysocka M.   +6 more
europepmc   +1 more source

Beyond Simple Mimicry: Next-Generation Geometric Architectures and Future Paradigms in Small-Molecule and Macrocyclic Peptidomimetics. [PDF]

Angew Chem Int Ed Engl
Lee J, Son S, Yoo JY, Lee JH, Chun M, Park SB.   +5 more
europepmc   +1 more source

Dual Amino Acid Swap in MUC7-Derived Peptide Enhances Resistance and Modulates Zn(II) and Cu(II) Complex Stability, Secondary Structure and Antimicrobial Activity. [PDF]

Inorg Chem
Szarszoń K, Kachnowicz J, Janek T, Domínguez-Martin A, Jezierska A, Wątły J.   +5 more
europepmc   +1 more source