Results 111 to 120 of about 19,199 (236)
Protein Science, Volume 35, Issue 5, May 2026.Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska +6 more
wiley +1 more source
A pyrene-functionalized triazole-linked hexahomotrioxacalix[3]arene as a fluorescent chemosensor for Zn²⁺ ions [PDF]
, 2016 A new pyrenyl appended hexahomotrioxacalix[3]arene L featuring 1,2,3-triazole linkers was synthesized as a fluorescent chemosensor for Zn²⁺ in mixed aqueous media. It exhibited high affinity toward Zn²⁺, and the monomer and excimer emission of the pyrene
Ikejiri, Yusuke +7 more
core +2 more sources
Andrology, Volume 14, Issue 4, Page 978-991, May 2026.Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre +5 more
wiley +1 more source
Synthesis of a Carbon‐Linked Acyldepsipeptide Derivative
European Journal of Organic Chemistry, Volume 29, Issue 15, 22 April 2026.The synthesis of a methylene‐linked acyldepsipeptide (ADEP) is reported. Success relied upon an improve method to generate a versatile vinyl glycine methyl ester synthon and a rationally optimized Grubb’s metathesis. NMR and in silico studies revealed an unusual trans–trans proline orientation for this new unnatural ADEP analog, advancing the ...
Katelyn G. Stevens-Davis +6 more
wiley +1 more source
Editorial: Expansion of the Genetic Code: Unnatural Amino Acids and their Applications
Frontiers in Chemistry, 2022 Subhendu Sekhar Bag +2 more
doaj +1 more source
Structure‐ and Ligand‐Based Discovery of Novel 3‐Chymotrypsin‐Like Protease Nonpeptidomimetic Hits
ChemMedChem, Volume 21, Issue 7, 14 April 2026.A multistep virtual screening cascade, integrating shape‐based, ensemble docking, and quantitative structure–activity relationship (QSAR) models, was employed to screen 1.5 million compounds. This funnel identified a novel 3‐chymotrypsin‐like protease (3CLpro) inhibitor, LabMol‐499, which was experimentally validated using a Förster Resonance Energy ...
Sabrina Silva‐Mendonça +14 more
wiley +1 more source
Solid-Phase Synthesis and Circular Dichroism Study of β-ABpeptoids
Molecules, 2019 The development of peptidomimetic foldamers that can form well-defined folded structures is highly desirable yet challenging. We previously reported on α-ABpeptoids, oligomers of N-alkylated β2-homoalanines and found that due to the presence ...
Ganesh A. Sable +2 more
doaj +1 more source
Car indoor air pollution - analysis of potential sources [PDF]
, 2011 The population of industrialized countries such as the United States or of countries from the European Union spends approximately more than one hour each day in vehicles.
Groneberg, Jan David Alexander +3 more
core
Computer-aided design of amino acid-based therapeutics: a review
Drug Design, Development and Therapy, 2018 Tayebeh Farhadi,1 Seyed MohammadReza Hashemian1,2 1Chronic Respiratory Diseases Research Center (CRDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran; 2Clinical ...
Farhadi T, Hashemian SM
doaj