Results 131 to 140 of about 14,095 (224)

Design, Synthesis, and Evaluation of Novel Thiazole-Based Peptidomimetic Compounds as Potent SARS-CoV-2 Main Protease Covalent Inhibitors. [PDF]

ACS Infect Dis
Yin W, Kong WP, Leung SL, Liang Z, Chen YW, Wong KY.   +5 more
europepmc   +1 more source

Efficient Method for High-Throughput Screening of Compound Libraries Targeting Human PD-L1. [PDF]

ACS Omega
Zamani MR, Čermáková K, Hadzima M, Šácha P, Konvalinka J.   +4 more
europepmc   +1 more source

Targeted sortase A inhibition by novel peptidomimetic antivirulents against staphylococcal infections. [PDF]

Microbiol Spectr
Hintzen JCJ, Rahimi S, Tietze D, Zhang J, Mehra P, Mijakovic I, Tietze AA.   +6 more
europepmc   +1 more source

Nicotine-Inspired, De Novo-Designed SARS-CoV-2 Main Protease Inhibitors Reveal Unique Chemistry for Covalently Conjugating Both Cysteine and Histidine Residues in the Catalytic Dyad. [PDF]

J Am Chem Soc
Atla S, Vulupala V, Alugubelli YR, Blankenship LR, Yang K, Nyalata S, Khatua K, Coleman D, Rabie D, Guo X, Cho CD, Kumar S, Le LHS, Sankaran B, Kalugin JK, Sharma S, Neuman BW, Xu S, Liu WR.   +18 more
europepmc   +1 more source

Therapeutic potential and safety challenges of antimicrobial peptides and peptidomimetics against ESKAPEE pathogens: a systematic review with quantitative analysis. [PDF]

J Antimicrob Chemother
Mekonen ES, Mishra SK, Urmi UL, Yeshtila YM, Maulvi FA, Kumar N, Willcox MDP.   +6 more
europepmc   +1 more source

Beyond proteolysis: rational modification of mucin-derived peptidomimetics with enhanced metal-mediated antimicrobial activity. [PDF]

RSC Adv
Ślusarczyk A, Bellotti D, Leveraro S, Janek T, Zobi F, Remelli M, Wątły J.   +6 more
europepmc   +1 more source

Evidence of an activity-enhancing conformational shift in Arabidopsis thaliana plant cysteine oxidase 4 induced by binding of substrate or substrate-mimics. [PDF]

J Biol Chem
Latter R, Hintzen JCJ, Shah LMN, Gunawardana DM, Sher RM, White MD, Mecinović J, Benesch JLP, Flashman E.   +8 more
europepmc   +1 more source

Recent Advances in the Design of Inhibitors Targeting the Viral Entry and Replication of the SARS-CoV-2 Virus, Driven by In Silico Approaches. [PDF]

Molecules
Nodola P, Molefe PSS, Tseki PF, Gumede NJ.   +3 more
europepmc   +1 more source

Deconvolution of the On-Target Activity of Plasmepsin V Peptidomimetics in <i>Plasmodium falciparum</i> Parasites. [PDF]

ACS Infect Dis
Su W, Nguyen W, Siddiqui G, Dziekan JM, Marapana D, Penington JS, Mehra S, Razook Z, McCann K, Ngo A, Jarman KE, Barry AE, Papenfuss AT, Gilson PR, Creek DJ, Cowman AF, Sleebs BE, Dans MG.   +17 more
europepmc   +1 more source

Peptidomimetic Modified Heptamethine Cyanine Dyes for Enhanced Bioimaging Targetability: A Molecular Interaction Study on Bovine Serum Albumin and Human Parvalbumin. [PDF]

J Med Chem
Ahmed TE, Azizi-Khereshki N, Henary M.
europepmc   +1 more source