Results 131 to 140 of about 12,487 (241)
Immunology, Volume 178, Issue 2, Page 249-260, June 2026.Schematic overview of the roles triggering receptor expressed on myeloid cells‐1 (TREM‐1) plays in monosodium urate (MSU) crystal‐induced inflammasome activation and IL‐1β secretion in gout arthritis. The present study provides novel data suggesting that blockade of TREM‐1 by LP17 attenuates MSU‐crystal‐induced inflammation through inhibition of ...
Yair Molad +2 more
wiley +1 more source
, 2013 aAbility of plasma to interact synergistically with peptidomimetic 1.
Line Hein-Kristensen (454385) +3 more
core +1 more source
Synthesis of a peptidomimetic analog of the binding domain of rapamycin
, 1997 Stereoselective synthesis of a peptidomimetic analog of the binding domain of rapamycin starting from N,N-dibenzyl-R-alaninal is ...
Azhar Hussain, Khaja +1 more
core +1 more source
Synthesis of a [1,4]dioxane-2,5-dione based-peptidomimetic scaffold [PDF]
, 2006 Copyright © ARKAT USA, Inc The document attached has been archived with permission from the publisher.(2S,3S)-3-[N-Cbz-L-Leucinyl]amino-2-hydroxy-4-phenylbutanoic acid 5 dimerised on treatment with EDCI and HOBT to give the symmetrical [1,4]dioxane-2,5 ...
Harvey, A., Abell, A.
core
γ4-Aminoxy peptides as new peptidomimetic foldamers
, 2004 The conformational properties of peptides 1-3 of γ-aminoxy acids have been investigated by using FT-IR, NMR spectroscopy, and X-ray crystallography. Diamide 1 consisting of unsubstituted γ-aminoxy acid cannot form intramolecular hydrogen bond.
Yang, D, Zhu, NY, Chen, F
core +1 more source
An α-Helical Peptidomimetic Inhibitor of the HIV-1 Rev−RRE Interaction
, 2016 The interaction between the HIV-1 Rev protein and the Rev-Responsive Element (RRE) RNA is an attractive target for anti-viral therapy. We have designed α-helical peptidomimetics of Rev-like peptides using side chain−side chain macrolactam formation ...
Matthew D. Daugherty (569680) +3 more
core +1 more source
Computer-aided design of amino acid-based therapeutics: a review
Drug Design, Development and Therapy, 2018 Tayebeh Farhadi,1 Seyed MohammadReza Hashemian1,2 1Chronic Respiratory Diseases Research Center (CRDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran; 2Clinical ...
Farhadi T, Hashemian SM
doaj
, 2020 The ability of a peptidomimetic (SC-67655) to block the peptide binding site of the rheumatoid arthritis-linked human leukocyte antigen encoded by the DRB1*0401 allele was evaluated.
Susan C Howard +12 more
core
Photosensitive Peptidomimetic for Light-Controlled, Reversible DNA Compaction
, 2016 Light-induced DNA compaction as part of nonviral gene delivery was investigated intensively in the past years, although the bridging between the artificial light switchable compacting agents and biocompatible light insensitive compacting agents was not ...
Svetlana Santer (1559020) +23 more
core +1 more source
, 2005 The 3,5,5-pyrrolin-4-one peptidomimetic scaffold was designed and developed in the laboratories of Professor Amos B. Smith, III and Professor Ralph Hirschmann, as a novel nonpeptide peptidomimetic for the β-strand conformation of peptides and proteins ...
Charnley, Adam Kenneth
core