Results 151 to 160 of about 14,095 (224)

Targeting collagen biosynthesis by small molecules inhibiting the function of the peptide-substrate-binding domain of collagen prolyl 4-hydroxylases. [PDF]

Sci Rep
Adediran B, Vela-Rodríguez C, Murthy S, Rahman MM, Wierenga RK, Lehtiö L, Koski MK.   +6 more
europepmc   +1 more source

The activity of a new bicyclic peptide, PLP-3, against colistin-resistant <i>Pseudomonas aeruginosa</i> biofilms. [PDF]

Biofilm
Martín-Vilardell N, Higazy D, Ballesté-Delpierre C, Vila J, Høiby N, Ciofu O.   +5 more
europepmc   +1 more source

Role of Structural Modifications in Peptidomimetic Compounds as Potential Antimicrobial Agents against <i>Staphylococcus aureus</i> and <i>Streptococcus pyogenes</i>: Balancing Bioavailability, Safety, and Antimicrobial Activity. [PDF]

ACS Omega
Dzierżyńska M, Sawicka J, Łada K, Gajewicz-Skretna A, Deptuła M, Chernobrovkin A, Pogorzelska A, Grubb A, Zubarev RA, Pikuła M, Kasprzykowski F, Rodziewicz-Motowidło S.   +11 more
europepmc   +1 more source

Conformational free energy landscape of sorting signal peptides in complex with bacterial sortases. [PDF]

Biophys J
Croney KA, Huisman C, Brock R, Whitham KM, Amacher JF, McCarty J.   +5 more
europepmc   +1 more source

Novel macrocyclic peptidomimetics targeting the insulin-regulated aminopeptidase (IRAP): design, synthesis and evaluation. [PDF]

RSC Med Chem
Olaniran Håkansson E, Balestri LJI, Puthiyaparambath S, Moes S, Henschel H, Sköld C, Hallberg M, Larhed M, Skillinghaug B, Odell LR.   +9 more
europepmc   +1 more source

Preclinical characterization of EGT710, an oral non-peptidomimetic reversible covalent SARS-CoV-2 main protease inhibitor. [PDF]

NPJ Drug Discov
Moquin SA, Lakshminarayana SB, Balavenkatraman KK, Schiller H, Claas A, Bhhatarai B, Loisios-Konstantinidis I, Vulic K, Kurhade C, Kalveram BK, Chen JY, Zou J, Xie X, Tandeske L, Dovala D, Ornelas E, Knapp MS, Fuller D, Nguyen Z, Barkan DT, Bebrevska L, Wright SK, Busby SA, Blais J, Shi PY, Gaudet S, Bergeron R, Yu H, Zack J, Sarko C, Gu F, Bradner JE, Tallarico JA, Diagana TT, Papillon JPN.   +34 more
europepmc   +1 more source

A Polyproline Type II Peptidomimetic Disrupts a Grb2 SH3C Domain Protein-Protein Interaction Implicated in Breast Cancer. [PDF]

Chembiochem
Luccarelli J, Simister PC, Hamilton AD, Feller SM, Thompson S.   +4 more
europepmc   +1 more source

Polymer- and peptide-based antiviral surface coatings: progress, mechanistic gaps, and future directions. [PDF]

Appl Environ Microbiol
Urmi UL, Willcox MDP.
europepmc   +1 more source

The Role of Zinc and Junctional Adhesion Molecule A Protein in Platelet Plug Formation. [PDF]

Medicines (Basel)
Nagidi SH, Stringham J, Firth E, Lisonbee B, Hart C, Mizrachi D.   +5 more
europepmc   +1 more source

Rational Design of Broad-Spectrum Anti-Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors. [PDF]

Adv Sci (Weinh)
Fang Y, Xie X, Fan H, Wu B, Wang A, Dai W, Liu Z, Li J, Tong H, Li J, Ren Y, Wang J, Zhou X, Liu H.   +13 more
europepmc   +1 more source