Results 151 to 160 of about 12,487 (241)

Next-generation inhibitors of SARS-CoV-2 M^pro overcome the deficiencies of Paxlovid. [PDF]

Nat Commun
Luo G, Wang G, Liao C, Zhong B, Fan L, Zhang J, Rao J, Zhang J, Wang Z, Luo M, Yan Y, Lu L, Xu W, Wu F, Gao X, Lu W.   +15 more
europepmc   +1 more source

Design and In Vitro Evaluation of Novel GC373-like SARS-CoV-2 Main Protease Inhibitors. [PDF]

Curr Issues Mol Biol
Kuznetsova AA, Makhin AP, Bulygin AA, Andrianova AA, Miturich VS, Zagitova RI, Shmygarev VI, Fadeeva AA, Yatskin ON, Belozerova OA, Smirnov IV, Yampolsky IV, Kaskova ZM, Kuznetsov NA.   +13 more
europepmc   +1 more source

Potent peptidomimetics [PDF]

Nature Biotechnology, 1999
openaire   +1 more source

Role of Structural Modifications in Peptidomimetic Compounds as Potential Antimicrobial Agents against <i>Staphylococcus aureus</i> and <i>Streptococcus pyogenes</i>: Balancing Bioavailability, Safety, and Antimicrobial Activity. [PDF]

ACS Omega
Dzierżyńska M, Sawicka J, Łada K, Gajewicz-Skretna A, Deptuła M, Chernobrovkin A, Pogorzelska A, Grubb A, Zubarev RA, Pikuła M, Kasprzykowski F, Rodziewicz-Motowidło S.   +11 more
europepmc   +1 more source

Novel macrocyclic peptidomimetics targeting the insulin-regulated aminopeptidase (IRAP): design, synthesis and evaluation. [PDF]

RSC Med Chem
Olaniran Håkansson E, Balestri LJI, Puthiyaparambath S, Moes S, Henschel H, Sköld C, Hallberg M, Larhed M, Skillinghaug B, Odell LR.   +9 more
europepmc   +1 more source

A Polyproline Type II Peptidomimetic Disrupts a Grb2 SH3C Domain Protein-Protein Interaction Implicated in Breast Cancer. [PDF]

Chembiochem
Luccarelli J, Simister PC, Hamilton AD, Feller SM, Thompson S.   +4 more
europepmc   +1 more source

Peptidomimetic α,β-Unsaturated Ethyl Esters Are Irreversible Inactivators of Human Cathepsin L and Are Potent Inhibitors of SARS-CoV-2 in Cellular Models of COVID-19. [PDF]

J Med Chem
Kumar V, Drelich A, Chenna BC, Rademacher A, Kemp AM, Bishop AC, Saenkham-Huntsinger P, Scott E, Wand AJ, Laganowsky A, Tseng CT, Meek TD.   +11 more
europepmc   +1 more source

Machine Learning-Guided Repositioning of a SARS-CoV-2-Targeting Molecular Series as Cruzain Inhibitors. [PDF]

ChemMedChem
Lameiro RF, Barbosa LF, Cardoso ER, Ho BS, Martins FCP, de Melo BC, Rosini F, Shamim A, Souza PM, de Souza WF, Montanari CA.   +10 more
europepmc   +1 more source

Structure-Guided SOCS3 Peptidomimetics: Design and Functional Characterization. [PDF]

ACS Omega
Cugudda A, La Manna S, Bucciero C, Castellano G, Malfitano AM, Marasco D.   +5 more
europepmc   +1 more source

Interleukin-11: A pivotal player and potential therapeutic target in prostate cancer. [PDF]

Curr Urol
Zhong J, Duan X, Wei Z, Zhu W, Zhao Z, Zeng G.   +5 more
europepmc   +1 more source