Results 141 to 150 of about 12,487 (241)

Editorial: Contemporary Perspective on 5-HT2C Receptor Function and Its Pharmacological Targeting

Frontiers in Pharmacology, 2020
Philippe De Deurwaerdère, Abdeslam Chagraoui, Abdeslam Chagraoui, Kathryn A. Cunningham   +3 more
doaj   +1 more source

Design, Synthesis, and Evaluation of Novel Thiazole-Based Peptidomimetic Compounds as Potent SARS-CoV-2 Main Protease Covalent Inhibitors. [PDF]

ACS Infect Dis
Yin W, Kong WP, Leung SL, Liang Z, Chen YW, Wong KY.   +5 more
europepmc   +1 more source

Efficient Method for High-Throughput Screening of Compound Libraries Targeting Human PD-L1. [PDF]

ACS Omega
Zamani MR, Čermáková K, Hadzima M, Šácha P, Konvalinka J.   +4 more
europepmc   +1 more source

Nicotine-Inspired, De Novo-Designed SARS-CoV-2 Main Protease Inhibitors Reveal Unique Chemistry for Covalently Conjugating Both Cysteine and Histidine Residues in the Catalytic Dyad. [PDF]

J Am Chem Soc
Atla S, Vulupala V, Alugubelli YR, Blankenship LR, Yang K, Nyalata S, Khatua K, Coleman D, Rabie D, Guo X, Cho CD, Kumar S, Le LHS, Sankaran B, Kalugin JK, Sharma S, Neuman BW, Xu S, Liu WR.   +18 more
europepmc   +1 more source

Targeted sortase A inhibition by novel peptidomimetic antivirulents against staphylococcal infections. [PDF]

Microbiol Spectr
Hintzen JCJ, Rahimi S, Tietze D, Zhang J, Mehra P, Mijakovic I, Tietze AA.   +6 more
europepmc   +1 more source

Evidence of an activity-enhancing conformational shift in Arabidopsis thaliana plant cysteine oxidase 4 induced by binding of substrate or substrate-mimics. [PDF]

J Biol Chem
Latter R, Hintzen JCJ, Shah LMN, Gunawardana DM, Sher RM, White MD, Mecinović J, Benesch JLP, Flashman E.   +8 more
europepmc   +1 more source

Peptidomimetic Modified Heptamethine Cyanine Dyes for Enhanced Bioimaging Targetability: A Molecular Interaction Study on Bovine Serum Albumin and Human Parvalbumin. [PDF]

J Med Chem
Ahmed TE, Azizi-Khereshki N, Henary M.
europepmc   +1 more source

Deconvolution of the On-Target Activity of Plasmepsin V Peptidomimetics in <i>Plasmodium falciparum</i> Parasites. [PDF]

ACS Infect Dis
Su W, Nguyen W, Siddiqui G, Dziekan JM, Marapana D, Penington JS, Mehra S, Razook Z, McCann K, Ngo A, Jarman KE, Barry AE, Papenfuss AT, Gilson PR, Creek DJ, Cowman AF, Sleebs BE, Dans MG.   +17 more
europepmc   +1 more source

On-Resin Synthesis and Diversification of Macrocyclic Disulfide Bridge Peptidomimetics via Bifunctional 5-Iodo-1,4-Triazoles. [PDF]

J Org Chem
Malone MA, Shepperson OA, Simms JE, Reid AJ, Jamieson AG.   +4 more
europepmc   +1 more source

Retraction Note: Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1. [PDF]

Sci Rep
Wang YJ, Patel BA, Anreddy N, Zhang YK, Zhang GN, Alqahtani S, Singh S, Shukla S, Kaddoumi A, Ambudkar SV, Talele TT, Chen ZS.   +11 more
europepmc   +1 more source