Results 111 to 120 of about 10,137 (233)
Peptidomimetics design and characterization: Bridging experimental and computer-based approaches
Peptidomimetics, designed to mimic peptide biological activity with more drug-like properties, are increasingly pivotal in medicinal chemistry. They offer enhanced systemic delivery, cell penetration, target specificity, and protection against peptidases
Samuele Di Cristofano +20 more
core +1 more source
Structure of the 4 peptidomimetics designed and synthesized.
Structure of the 4 peptidomimetics designed and synthesized.
Rong Chen (29176) +9 more
core +1 more source
Computer-aided design of amino acid-based therapeutics: a review
Tayebeh Farhadi,1 Seyed MohammadReza Hashemian1,2 1Chronic Respiratory Diseases Research Center (CRDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran; 2Clinical ...
Farhadi T, Hashemian SM
doaj
Engineering Stealth Properties of Fluorescent Polymeric Nanoparticles by Short‐Chain Polysarcosine
To define the minimal polysarcosine chain length required for nanoparticle stealth properties, we engineered dye‐loaded polymeric nanoparticles functionalized with 5‐, 11‐, or 19‐mer peptoids. Only nanoparticles with 19‐mer polysarcosine achieved near‐neutral zeta potential, suppressed nonspecific interactions with glass surface and live cells ...
Tanushree Gupta +9 more
wiley +1 more source
Synthesis of peptidomimetics comprising hydrazino - derivatives of amino acides [PDF]
Peptidi i proteini imaju ključnu ulogu u nizu bioloških i fizioloških procesa; međutim, njihova primjena kao terapeutika je ograničena slabom stabilnošću i biodostupnošću.
Suć, Josipa
core
Agonistic and antagonistic activities of the peptidomimetics against BdNTLR.
Agonistic and antagonistic activities of the peptidomimetics against BdNTLR.
Krzysztof Kaczmarek (3057564) +8 more
core +1 more source
Fungal‐Bacterial Interactions in Polymicrobial Infections: Hidden Threats
ABSTRACT Polymicrobial infections involving fungi and bacteria represent a major and increasingly recognized clinical challenge, in which interkingdom interactions significantly amplify disease severity, antimicrobial resistance, and treatment failure. Rather than passive co‐existence, fungal–bacterial communities form highly coordinated systems driven
Mohammad Javad Roustaye Gourabi +3 more
wiley +1 more source
Synthesis and Application of Triazole Containing Peptidomimetics
Kracker O. Synthesis and Application of Triazole Containing Peptidomimetics.
Kracker, Oliver
core
Peptidomimetics as a new generation of antimicrobial agents: current progress
Patricia Méndez-Samperio Department of Immunology, National School of Biological Sciences, National Polytechnic Institute, Mexico City, Mexico Abstract: Antibiotic resistance is an increasing public health concern around the world. Rapid increase
Méndez-Samperio P
doaj
APOE is widely recognized for its role in neurodegeneration and cardiovascular disease, but its different genotypes also influence body composition, affecting obesity, bone density, and muscle mass, through their central role in lipid transport and metabolism.
Miriam Frosina +5 more
wiley +1 more source

