Results 41 to 50 of about 11,685 (174)

Agonistic and antagonistic activities of the peptidomimetics against BdNTLR.

open access: yes, 2018
Agonistic and antagonistic activities of the peptidomimetics against BdNTLR.
Krzysztof Kaczmarek (3057564)   +8 more
core   +1 more source

Visualized and Quantitative Conformational Analysis of Peptidomimetics

open access: yes, 2021
Protein–protein interactions (PPIs) are fundamentally important and challenging drug targets. Peptidomimetic molecules of various types have been developed to modulate PPIs.
Hajime Takashima   +15 more
core   +1 more source

Facile green diversity-oriented synthesis, molecular docking, and cytotoxicity evaluation of quinoline -triazole appended peptidomimetics as inhibitors of human breast cancer cell line MCF-7

open access: yesResults in Chemistry
The synthesis of quinoline-based drugs has significant interest from researchers due to their broad spectrum of biological activities. In this context, a concise approach for the synthesis of quinoline-functionalized hybrid peptidomimetics is described ...
K. Ramya   +5 more
doaj   +1 more source

Development of Peptide Biopharmaceuticals in Russia

open access: yesPharmaceutics, 2022
Peptides are low-molecular-weight substances that participate in numerous important physiological functions, such as human growth and development, stress, regulation of the emotional state, sexual behavior, and immune responses.
Vladislav I. Deigin   +4 more
doaj   +1 more source

Structure of the 4 peptidomimetics designed and synthesized.

open access: yes, 2016
Structure of the 4 peptidomimetics designed and synthesized.
Rong Chen (29176)   +9 more
core   +1 more source

Venom peptides and peptidomimetics as therapeutics

open access: yes, 2022
In the last 10 years, antimicrobial resistance (AMR) has become a huge public health concern with an estimated 10 million deaths per year and a projected $100 trillion impact on global the economy.
Ahmad, Zulfiqar, Akhtar, Suhail
core   +1 more source

Biological Evaluation and Conformational Preferences of Ferrocene Dipeptides with Hydrophobic Amino Acids

open access: yesInorganics, 2023
Despite the large number of peptidomimetics with incorporated heteroannularly functionalized ferrocenes, few studies have investigated their bioactivity.
Monika Kovačević   +10 more
doaj   +1 more source

Synthesis and Application of Triazole Containing Peptidomimetics [PDF]

open access: yes, 2019
Kracker O. Synthesis and Application of Triazole Containing Peptidomimetics.
Kracker, Oliver
core  

Synthesis of Constrained Peptidomimetics via the Pictet-Spengler Reaction

open access: yes, 2016
Peptidomimetics offers a solution to the poor pharmacokinetic properties displayed by natural peptides, by providing pharmaceutically useful chemical structures with the ability to mimic the endogenous polyamide structure.
Vitaly V. Komnatnyy   +5 more
core   +1 more source

1H-Imidazole-2,5-Dicarboxamides as NS4A Peptidomimetics: Identification of a New Approach to Inhibit HCV-NS3 Protease

open access: yesBiomolecules, 2020
The nonstructural (NS) protein NS3/4A protease is a critical factor for hepatitis C virus (HCV) maturation that requires activation by NS4A. Synthetic peptide mutants of NS4A were found to inhibit NS3 function.
Abdelsattar M. Omar   +7 more
doaj   +1 more source

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