Results 41 to 50 of about 163,491 (263)

Die molekulare Logik der nichtribosomalen Peptidsynthetasen: Identifizierung und biochemische Charakterisierung der Biosynthesegene für Gramicidin A [PDF]

, 2005
Gramicidin ist ein Polypeptid, das aus 15 hydrophoben Aminosäuren mit alternierender L-D-Konfiguration besteht. In vivo bilden sich Homodimere, die in Membranen als Ionenkanäle fungieren.
Bölker, Michael (Prof. Dr.), Schracke, Nadine   +1 more
core   +1 more source

Associated bacteria affect sexual reproduction by altering gene expression and metabolic processes in a biofilm inhabiting diatom [PDF]

, 2019
Diatoms are unicellular algae with a fundamental role in global biogeochemical cycles as major primary producers at the base of aquatic food webs. In recent years, chemical communication between diatoms and associated bacteria has emerged as a key factor
Bilcke, Gust, Cirri, Emilio, De Decker, Sam, De Veylder, Lieven, Osuna, Cristina, Pohnert, Georg, Vandepoele, Klaas, Vyverman, Wim, Werner, Markus, Werz, Oliver   +9 more
core   +2 more sources

Secretome analysis revealed adaptive and non-adaptive responses of the Staphylococcus carnosus femB mutant

Proteomics, 2015
FemABX peptidyl transferases are involved in non‐ribosomal pentaglycine interpeptide bridge biosynthesis. Here, we characterized the phenotype of a Staphylococcus carnosus femB deletion mutant, which was affected in growth and showed pleiotropic effects ...
Mulugeta Nega, Linda Dube, M. Kull, A. Ziebandt, Patrick Ebner, D. Albrecht, B. Krismer, R. Rosenstein, M. Hecker, F. Götz   +9 more
semanticscholar   +1 more source

Ribozyme für die RNA‐katalysierte Methylierung und Markierung von RNA

Angewandte Chemie, EarlyView.
Ribozyme sind vielseitige Werkzeuge für die präzise Modifikation von RNA. Das Reaktionsspektrum in‐vitro‐selektierter Ribozyme reicht vom Einbau funktioneller Gruppen und Fluorophoren bis zu natürlichen RNA‐Methylierungen. Dieser Übersichtsartikel präsentiert Cofaktor‐abhängige Ribozyme für die positionsgenaue Markierung und Modifikation von RNA ...
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source

Characterization of the Arabidopsis thaliana 2-Cys peroxiredoxin interactome [PDF]

, 2016
This document is the Accepted Manuscript of the following article: Delphine Cerveau, et al, ‘Characterization of the Arabidopsis thaliana 2-Cys peroxiredoxin interactome’, Plant Science, Vol. 252, pp.
Ahn, Alexandra Kraut, Awad, Baier, Baier, Balmer, Balmer, Balmer, Broin, Broin, Cai, Caporaletti, Cerveau, Chae, Chaturvedi, Chen, Chen, Chew, Cho, Coic, Collin, Dangoor, Day, Delphine Cerveau, Dietz, Dietz, Dietz, Dixon, Dixon, Dominguez-Solis, Eliyahu, Grant, Gutierrez-Marcos, Halliwell, Hattenbach, Henrik U. Stotz, Heukeshoven, Hong, Hudson, Jang, Johnston, Jung, Jönsson, Kim, Kim, Kim, Kojima, König, Lamkemeyer, Laxa, Lee, Lemaire, Liebthal, Lindhal, Maeda, Marchand, Martin J. Mueller, Montrichard, Moon, Moon, Motohashi, Muhlbach, Muthuramalingam, Pascal Rey, Peltier, Perez-Ruiz, Phee, Puerto-Galan, Pulido, Qu, Ralat, Reed, Rey, Rey, Rey, Rhee, Richter, Sahrawy, Schürmann, Setya, Sirpio, Song, Stenbaek, Vizcaíno, Wagner, Whitney, Wong, Woo, Wood, Yamauchi, Yamauchi, Yohann Couté, Yu   +92 more
core   +4 more sources

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18:Enzymes [PDF]

, 2017
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
,, Alexander, Stephen Ph, Davies, Jamie A, Fabbro, Doriano, Faccenda, Elena, Harding, Simon D, Kelly, Eamonn, Marrion, Neil V, Pawson, Adam J, Peters, John A, Sharman, Joanna L, Southan, Christopher   +11 more
core   +15 more sources

The effect of gougerotin analogues on ribosomal peptidyl transferase

FEBS Letters, 1971
1. Introduction Gougerotin (I), a dipeptidyl pyrimidine nucleoside antibiotic, has been found to specifically inhibit the step of protein biosynthesis which is catalyzed by ribosomal peptidyl transferase [l-S] . Since three gougerotin analogues have been synthesized recently [6] , 1-[3(sarcosyl-D-seryl-)amino3-deoxy$-D-gluco- pyranosyl-)uracil (II, cf.
Černá, J., Lichtenthaler, F.W., Rychlík, I.   +2 more
openaire   +2 more sources

Peptidyl transferase center decompaction and structural constraints during early protein elongation on the ribosome

Scientific Reports, 2021
Peptide bond formation on the ribosome requires that aminoacyl-tRNAs and peptidyl-tRNAs are properly positioned on the A site and the P site of the peptidyl transferase center (PTC) so that nucleophilic attack can occur.
B. Jia, Tianlong Wang, J. Lehmann
semanticscholar   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

Angewandte Chemie International Edition, EarlyView.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source

Legionella: from protozoa to humans [PDF]

, 2011
International audiencePathogens that are able to enter and multi- ply within human cells are responsible for multiple diseases and millions of deaths worldwide.
Carmen Buchrieser
core   +1 more source