Results 61 to 70 of about 163,491 (263)

The competitive interplay of 12‐oxophytodienoic acid (OPDA), protein thiols, and glutathione

The FEBS Journal, EarlyView.
12‐Oxophytodienoic acid (OPDA) is a phytohormone involved in plant growth and stress defense. Due to its cyclopentenone moiety, OPDA can form Michael adducts with thiol‐containing compounds such as glutathione and cysteine residues of proteins, resulting in alterations of the cellular redox regulatory network.
Madita Knieper, Ruben Schwarz, Lara Vogelsang, Jens Sproß, Armağan Kaya, Maike Bittmann, Harald Gröger, Andrea Viehhauser, Karl‐Josef Dietz   +8 more
wiley   +1 more source

Properties and identification of antibiotic drug targets [PDF]

, 2010
Background: We analysed 48 non-redundant antibiotic target proteins from all bacteria, 22 antibiotic target proteins from E. coli only and 4243 non-drug targets from E.
Tala M Bakheet, Andrew J Doig, MC McManus, REW Hancock, DE Brodersen, AP Carter, F Schlunzen, A Maxwell, BG Spratt, FC Tenover, KR Sakharkar, S Rey, P Hu, T Nakama, T Izard, MW Vetting, J Kim, ED Brown, A Yonath, TM Bakheet, DS Wishart, GL Wang, J Kyte, M Ashburner, K Julenius, LJ Jensen, JD Bendtsen, A Krogh, JC Wootton, JA Cuff, VN Vapnik, L Li, SY Gerdes, SF Altschul   +33 more
core   +1 more source

Modulating the activity of the peptidyl transferase center of the ribosome [PDF]

RNA, 2008
The peptidyl transferase (PT) center of the ribosome catalyzes two nucleophilic reactions, peptide bond formation between aminoacylated tRNA substrates and, together with release factor, peptide release. Structure and function of the PT center are modulated by binding of aminoacyl-tRNA or release factor, thus providing the basis for the specificity of ...
openaire   +2 more sources

Kinetic and Mechanistic Characterization of Recombinant Lactobacillus viridescens FemX (UDP-N-acetylmuramoyl Pentapeptide-lysine N6-Alanyltransferase)*

Journal of Biological Chemistry, 2003
The FemABX family encodes enzymes that incorporate l-amino acids into the interchain peptide bridge of Gram-positive cell wall peptidoglycan and are novel nonribosomal peptidyl transferases that use aminoacyl-tRNA as the amino acid donor.
S. Hegde, J. Blanchard
semanticscholar   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Adaptation Mechanisms in the Evolution of Moss Defenses to Microbes [PDF]

, 2017
The tri-colored bat (Perimyotis subflavus) has declined severely across its range since 2006 due to white nose syndrome, a fungal disease causing massive bat mortality in North America.
Inés Ponce de León, Marcos Montesano
core   +3 more sources

RNA-Protein Mutually Induced Fit

Journal of Biological Chemistry, 2009
tRNAs that read codons starting with U are usually modified at their A37 by isopentenyl-tRNA transferases to minimize peptidyl-tRNA slippage in translation.
E. Seif, Martin Hallberg
semanticscholar   +1 more source

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

Plant, Cell &Environment, EarlyView.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz, Łukasz Marczak, Aleksander Strugała, Maria Tomys, Ewelina Ratajczak, Tomasz Skrzypczak, Przemysław Wojtaszek, Anna Kasprowicz‐Maluśki, Agnieszka Szuba   +8 more
wiley   +1 more source

Transcript correlation analysis for the identification of novel plant genes involved in iron metabolism and beyond: what next?

Plant Biology, EarlyView.
Transcript correlation analysis allowed the identification of several key nodes in the complex regulatory network of plant iron metabolism. Abstract Arabidopsis thaliana was the first plant genome to be fully sequenced, almost a quarter of a century ago, thanks to The Arabidopsis Genome Initiative, with contributions from scientists worldwide.
I. Murgia, P. Morandini
wiley   +1 more source

Association mapping for hop cone chemistry and morphology identifies natural beneficial allele stacks

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Efforts are underway to increase the efficiency and precision of selection hop (Humulus lupulus L.) breeding using genomics. Little is known, however, about the genetic control of important traits like α‐and β‐acids contents, oil content, and cone morphological characteristics, all of which play an important role in determining the utility and
Shaun J. Clare, Peter Schmuker, Kayla Altendorf   +2 more
wiley   +1 more source